Co-ordination & Response (Edexcel IGCSE Biology)

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  • What are some physiological factors controlled by homeostasis in mammals?

    Physiological factors that are controlled in mammals include:

    • Core body temperature

    • Metabolic waste concentrations, e.g. carbon dioxide and urea

    • Blood pH

    • Blood glucose concentration

    • Blood water content

    • Blood oxygen concentration

  • What are the two communication systems that allow mammals to respond to changes in their environment?

    The two systems that allow mammals to respond to changes in their environment are:

    • The nervous system

    • The endocrine system

  • True or False?

    Blood pH must be kept constant to prevent negative effects on enzyme activity.

    True.

    Regulation of blood pH is important to maintain optimum enzyme activity. Enzymes may become denatured if pH moves away from optimum.

  • Define the term homeostasis

    Homeostasis is the maintenance of a constant internal environment within narrow limits.

  • Why is homeostasis important for organisms?

    Homeostasis is vital to organisms because it maintains conditions that support enzyme activity and cellular function.

  • True or False?

    Core body temperature in humans is maintained at around 37 °C.

    True.

    Core body temperature in humans is around 37 °C. This is the optimum temperature for enzyme activity in the human body.

  • True or False?

    Enzymes may become denatured if core body temperature increases too much.

    True.

    High temperatures can result in denaturing of enzymes. This means the shape of the active site changes and no longer fits with the substrate.

  • What happens to animal cells if blood water content is not maintained within narrow limits?

    If blood water content is not maintained within narrow limits then the following may occur:

    • If blood water content is too high water will move into cells by osmosis and cells may burst

    • If blood water content is too low water will move out of cells by osmosis and the cells will shrink

  • Define the term stimulus.

    A stimulus is a change in environmental conditions, e.g. a change in blood glucose levels.

  • What are receptor cells?

    Receptor cells are cells that detect stimuli, e.g. cells in the eyes detect changes in light levels.

  • True or False?

    Effectors detect environmental stimuli and transmit this information to the receptors.

    False.

    Receptor cells detect changes (stimuli) and transmit this information to the coordination centre, which then processes the information and sends signals to effectors to carry out responses.

  • Define the term effector.

    An effector is a muscle or gland that brings about a response in order to restore normal conditions in the body.

  • True or False?

    A coordinated response involves a stimulus, a receptor and an effector.

    True.

    Coordinated responses require a stimulus (environmental change), receptor cells (to detect stimuli) and an effector (to carry out responses and restore optimal conditions). There will also be a coordination centre to process information.

  • Define the term coordination centre.

    A coordination centre, such as the brain or spinal cord, receives and processes information from receptors and initiates responses that restore optimal conditions in the body.

  • Which effector releases oestrogen as part of the menstrual cycle?

    The effector that releases oestrogen is the ovaries. Oestrogen is released in the menstrual cycle in response to the hormone FSH.

  • Why do plants need to respond to stimuli such as light and gravity?

    Plants need to respond to stimuli to ensure that they can maximise their growth, e.g.

    • Responding to light ensures their leaves can absorb maximum light energy for photosynthesis.

    • Responding to gravity ensures that shoots grow upwards towards light and roots grow downwards towards water and mineral ions.

  • Define the term tropism.

    Tropisms are directional growth responses to stimuli, such as light and gravity, in plants.

  • What is a positive tropism?

    A positive tropism occurs when a plant grows towards a stimulus, e.g. growing towards light.

  • What is a negative tropism?

    A negative tropism occurs when a plant grows away from a stimulus, e.g. growing against gravity.

  • True or False?

    Positive geotropism results in upward growth away from gravity.

    False.

    Positive geotropism will result in downward growth that is towards gravity; this would occur in roots. Growth away from gravity occurs in shoots and is known as negative geotropism.

  • Define the term phototropism.

    Phototropism is the directional growth of plants in response to light, allowing shoots to grow towards light to optimise photosynthesis.

  • Define the term geotropism (or gravitropism).

    Geotropism, also known as gravitropism, is the directional growth response of plants in relation to gravity; roots grow downwards and shoots grow upwards.

  • True or False?

    Shoots show a positive phototropic response and a negative geotropic response.

    True.

    Shoots exhibit positive phototropism by growing towards light, and negative geotropism by growing away from gravity.

  • True or False?

    Roots show a negative phototropic response and a positive geotropic response.

    True.

    Roots demonstrate negative phototropism by growing away from light, and positive geotropism by growing towards gravity.

  • True or False?

    Auxin is often described as a plant hormone.

    True.

    Auxin is a growth regulator that alters the growth of plants; it is sometimes referred to as a plant hormone.

  • What effect does auxin have on cells in the shoots of plants?

    Auxin stimulates cell elongation in plant shoots.

  • What happens to auxin distribution when light shines on one side of a shoot?

    When light shines on one side of a shoot the auxin produced in the tip accumulates on the shaded side, causing faster elongation and growth of cells on the shaded side compared to the sunny side.

  • How does auxin distribution in response to light lead to phototropism?

    Auxin accumulation on the shaded side of a shoot causes cells on the shady side to elongate at a faster rate than cells on the light side; this leads to bending of the shoot towards the light.

  • What will happen to the growth of a plant shoot that received even light on all sides?

    A shoot that receives even light on all sides will grow straight upwards. This is because auxin would be evenly distributed and so cell elongation would occur at the same rate in all cells.

  • How would auxin be distributed if a plant was placed in a dark room?

    If a plant was placed in a dark room auxin would be evenly distributed and so the plant shoots would continue to grow straight upwards.

  • How does information travel through the nervous system?

    Information is transmitted through the nervous system along neurones in the form of electrical impulses.

  • How is information transmitted by the endocrine system?

    Information is transmitted by the endocrine system when hormones are carried by the blood to target cells.

  • True or False?

    Hormones are used to control functions that require instant responses.

    False.

    Hormones are used to control functions that do not require instant responses; this is because hormonal transmission is slow in comparison to nervous transmission.

  • What are some examples of hormone glands?

    Examples of hormone, or endocrine, glands include:

    • Ovaries

    • Testes

    • Pituitary gland

    • Pancreas

    • Adrenal gland

  • True or False?

    Hormones can affect any cell of the body.

    False.

    Hormones only affect specific target cells because they bind to receptors which are only present on the surface of these target cells.

  • True or False?

    Responses of the endocrine system are long-lived compared to responses of the nervous system.

    True.

    Hormonal responses can be very long-lived, while the effect of a nerve impulse stops as soon as impulse transmission stops.

  • Which two organs make up the central nervous system (CNS)?

    The CNS is made up of the brain and the spinal cord.

  • True or False?

    A bundle of neurones is known as a gland.

    False.

    A bundle of neurones is known as a nerve.

  • What is the role of the central nervous system?

    The role of the central nervous system is to receive information from the senses and coordinate a response.

  • What is the function of a sensory neurone?

    Sensory neurones carry impulses from sense organs to the central nervous system (CNS).

  • True or False?

    Motor neurones carry impulses from effectors to the central nervous system (CNS).

    False.

    Motor neurones carry impulses from the CNS to effectors (muscles or glands).

  • True or False?

    The myelin sheath insulates axons and prevents nerve impulses from travelling too fast.

    False.

    The myelin sheath insulates axons in order to increase the speed at which nerve impulses are transmitted.

  • Write a flow diagram to show the pathway of an electrical impulse through the nervous system.

    The pathway of an impulse is as follows:

    stimulus → receptor → sensory neurone → CNS → motor neurone → effector → response

  • Give two examples of stimuli which would trigger a response via the nervous system.

    Examples of stimuli which would trigger a response via the nervous system include:

    • Light

    • Sound

    • Touch / pressure / pain

    • Temperature

    • Chemicals, e.g. in the air or in food/drink

  • What happens when a receptor is stimulated?

    When a receptor is stimulated an electrical impulse is sent along sensory neurones towards the central nervous system (CNS).

  • True or False?

    The effector is the first component to receive information about a stimulus.

    False.

    The effector is the part of the body that carries out the response, so it is the last component to receive information about a stimulus. The first component would be the receptor.

  • What is the role of a receptor in the nervous system?

    Receptors are specialised cells that detect specific stimuli and convert them into electrical impulses, initiating the transmission of signals through the nervous system.

  • True or False?

    Relay neurones are only found in the central nervous system.

    True.

    Relay neurones are found in the central nervous system. They connect sensory neurones to motor neurones.

  • Define the term synapse.

    A synapse is a junction between two neurones where a very small gap exists between one neurone and the next.

  • Define the term neurotransmitter.

    Neurotransmitters are chemical signalling molecules used to transfer signals between neurones at synapses.

  • True or False?

    Electrical impulses can jump across the gap at a synapse.

    False.

    Electrical impulses cannot directly jump the gap at synapses. Electrical signals are converted into chemical signals in the form of neurotransmitters.

  • How is an impulse passed across a synapse?

    An electrical impulse travels across the gap at a synapse as follows:

    • Neurotransmitters are released and diffuse across the gap between neurones

    • Neurotransmitters bind to receptor molecules on the second neurone

    • A new electrical impulse is generated in the second neurone

  • True or False?

    Neurotransmitters move across the synapse by active transport.

    False.

    Neurotransmitters move across the gap at a synapse by diffusion from a high concentration to a low concentration.

  • What happens to neurotransmitters after impulse transmission at a synapse has finished?

    After impulse transmission has finished the neurotransmitters are broken down by enzymes to prevent continuous stimulation of the second neurone.

  • True or False?

    Reflex responses involve conscious processing in the brain.

    False.

    Reflex responses do not involve conscious processing in the brain; they are automatic and rapid, meaning that the brain may not become consciously aware of the stimulus until after the body has responded.

  • Define the term reflex.

    A reflex is an involuntary reaction that does not involve conscious processing in the brain. It is automatic, rapid, and helps minimise damage to the body.

  • What is an example of a reflex response?

    Examples of reflex responses include:

    • Pain-withdrawal, e.g. removing a hand from a hot or sharp object

    • Blinking

    • The pupil reflex

    • Coughing

    • The knee-jerk reflex

  • Write a flow diagram to show the pathway of a reflex arc when withdrawing from a hot object.

    In a reflex arc for withdrawing from a hot object the pathway is as follows:

    Hot object (stimulus) → sensory neurone → relay neurone in spinal cord → motor neurone → muscle (effector) → contraction to move away from object (response)

  • What are the three types of neurone involved in a reflex arc?

    The three types of neurone in a reflex arc are:

    • Sensory neurones carry impulses to the CNS

    • Relay neurones connect sensory and motor neurones within the CNS

    • Motor neurones carry impulses from the CNS to effectors

  • What role does the spinal cord play in a reflex arc?

    The spinal cord acts as the coordinator in a reflex arc, receiving sensory input and generating motor output without involving the conscious brain.

  • Where are the synapses located in a reflex arc?

    Synapse occur where signals are transmitted from one neurone to another; in a reflex arc this would be:

    • Between sensory and relay neurones

    • Between relay and motor neurones

  • Why are reflex responses important?

    Reflex responses are important because they are quick and automatic, allowing the body to avoid injury.

  • Name the light-sensitive receptor cells found in the retina of the eye.

    The receptor cells in the retina which are sensitive to light are rods and cones.

  • What is the function of the optic nerve?

    The optic nerve is responsible for transmitting electrical impulses from the receptor cells in the retina to the brain.

  • What is the role of the fovea in the retina?

    The fovea is a region of the retina with the highest density of cones; light focused here results in detailed, colour vision.

  • True or False?

    The iris is made up of muscles that control the light entering the eye.

    True.

    The circular and radial muscles of the iris contract and relax to alter the light that can enter the eye through the pupil.

  • What is the role of the cornea in the eye?

    The cornea is a transparent layer located on the surface of the eye. It provides protection and plays a role in focusing light onto the retina.

  • Define the term blind spot in relation to the eye.

    The blind spot is the area where the optic nerve exits the retina; it lacks receptor cells, thus creating a spot where no vision occurs.

  • Name the stimulus which is detected by the eye.

    The eye is a highly specialised sense organ which detects light stimuli.

  • True or False.

    The optic nerve is made up of motor neurones.

    False.

    The optic nerve is made up of sensory neurones which transmits electrical impulses from the receptors in the retina to the brain.

  • What is the role of the suspensory ligaments in the eye?

    The suspensory ligaments connect the ciliary muscle to the lens, facilitating changes in lens shape during accommodation. This allows the eye to focus on near or distant objects.

  • Which receptor cells are affected in those with colour blindness?

    The receptor cells that are affected in colour blindness are the cone cells. These are the receptors which are responsible for detecting light wavelength, so they provide colour vision.

  • Define the term accommodation in the context of eye function.

    Accommodation is the process by which the lens of the eye changes its shape to focus on objects at different distances. It is facilitated by the contraction or relaxation of the ciliary muscles and adjustment of the suspensory ligaments.

  • Define the term refraction.

    Refraction is the bending of light as it enters a medium of a different density, e.g. the lens of the eye.

  • Name the two components of the eye that are responsible for refracting light.

    Two structures of the eye which are responsible for refraction of light are:

    • Cornea

    • Lens

  • What is the role of the ciliary muscle in accommodation?

    The ciliary muscle controls the shape of the lens by contracting to thicken it during close vision and relaxing to flatten it during distant vision. This is known as accommodation.

  • What happens to the lens and ciliary muscles when focusing on a near object?

    When focusing on a near object:

    • The ciliary muscles contract

    • The suspensory ligaments loosen

    This causes the lens to become thicker (more curved), increasing refraction of light for close vision.

  • True or False?

    When focusing on a distant object the ciliary muscles relax and the suspensory ligaments loosen.

    False.

    When focusing on a distant object:

    • The ciliary muscles relax

    • The suspensory ligaments tighten

    This pulls on the lens, making it thinner and less curved; this reduces refraction of light for distant vision.

  • What is the purpose of the pupil reflex?

    The pupil reflex protects the retina from damage in bright light or improves vision in dim light. It does this by adjusting the size of the pupil to control the light entering the eye.

  • Name the antagonistic muscle pair which is responsible for the pupil reflex.

    The antagonistic muscle pair responsible for the pupil reflex is the:

    • Circular muscles

    • Radial muscles

    Both of these muscles are found in the iris of the eye.

  • True or False?

    The radial muscles contract in response to dim light.

    True.

    Radial muscles contract and the circular muscles relax in response to dim light. This results in dilation of the pupil to allow more light to reach the retina.

  • What changes occur in the pupil when exposed to bright light?

    In bright light the circular muscles contract and the radial muscles relax. This causes the pupil to constrict, reducing the light entering the eye and protecting the retina from damage.

  • Why is temperature regulation in mammals important?

    Temperature regulation ensures that core temperature stays at around 37 °C. This maintains optimal enzyme activity and therefore efficient physiological function.

  • How does sweating increase heat loss from the body?

    Sweating increases heat loss when sweat evaporates from the skin surface. The evaporation of sweat transfers heat energy away from the skin.

  • Define the term vasodilation.

    Vasodilation is a cooling mechanism in which the diameter of skin arterioles increases. This increases blood flow to capillaries in the skin surface, transferring heat to the environment by radiation.

  • How do blood vessels and sweat glands respond to an increased body temperature?

    An increase in body temperature leads to the following changes:

    • Sweat glands release sweat which cools the skin by evaporation

    • Skin arterioles undergo vasodilation to increase blood flow to the capillaries at the surface of the skin

  • True or False?

    Vasodilation occurs during exercise.

    True.

    Exercise raises core body temperature due to increased metabolic activity in the contracting muscles. Sweating and vasodilation occur as part of the temperature regulation mechanisms of the skin.

  • True or False?

    When a person enters a colder environment blood flow to the surface of the skin is reduced.

    True.

    Vasoconstriction is a heat retention mechanism. The diameter of skin arterioles decreases to reduce blood flow to capillaries in the surface of the skin. This minimises heat loss by radiation.

  • How does shivering contribute towards temperature regulation?

    Shivering aids temperature regulation because the rapid muscle contractions generate heat through respiration; this helps to raise the core body temperature.

  • True or False?

    Constriction of the capillaries reduces blood flow to the surface of the skin.

    False.

    Capillaries do not have a muscle layer and therefore cannot constrict. Constriction occurs in the arterioles that supply the skin capillaries, reducing blood flow to the skin surface.

  • Define the term hormone.

    A hormone is a chemical messenger molecule released from glands and transported in the blood. Hormones bring about changes in specific target cells.

  • What is the function of adrenaline in the body?

    Adrenaline is known as the 'fight or flight' hormone and its role is to prepare the body for action. Its effects include:

    • Increased heart rate

    • Increased breathing rate

    • Diversion of blood flow to muscles

    • Breaking down glycogen to release glucose

  • Name the gland that produces and secretes insulin.

    The pancreas is the gland that produces and secretes insulin.

  • True or False?

    Insulin is a hormone that increases blood glucose levels.

    False.

    Insulin reduces blood glucose levels by increasing the uptake of glucose from the blood into the body cells, where it is converted into glycogen. Blood glucose levels increase in response to adrenaline.

  • What is the primary role of testosterone in males?

    Testosterone, produced in the testes, is responsible for the development of secondary sexual characteristics in males.

  • True or False?

    Progesterone is responsible for initiating the development of secondary sexual characteristics in females.

    False.

    Progesterone, produced in the ovaries, maintains the uterine lining during parts of the menstrual cycle and during pregnancy. Secondary sexual characteristics develop in females due to the action of oestrogen.

  • Name the hormone responsible for the development of secondary sexual characteristics in females.

    Oestrogen, produced by the ovaries, is responsible for the development of secondary sexual characteristics in females. It is also involved with regulation of the menstrual cycle.

  • Which homeostatic mechanism is regulated by the hormone ADH?

    Osmoregulation is the homeostatic mechanism regulated by ADH. It involves maintaining the balance of water and solutes in the blood.

  • How does the secretion of ADH change in response to blood water content?

    The secretion of ADH changes in response to blood water content as follows:

    • ADH secretion increases when blood water content is low

    • ADH secretion decreases when blood water content is high

  • True or False?

    Increased secretion of ADH increases water reabsorption in the nephrons of the kidney.

    True.

    Increased secretion of ADH increases water reabsorption in the nephrons when blood water content is low, resulting in production of concentrated urine.

  • Name the four hormones that are responsible for control of the menstrual cycle.

    The menstrual cycle is regulated by:

    • FSH

    • LH

    • Oestrogen

    • Progesterone

  • Describe the functions of FSH and LH in the menstrual cycle.

    The roles of FSH and LH in the menstrual cycle are:

    • FSH stimulates egg maturation in the ovary and stimulates the release of oestrogen

    • LH triggers ovulation

  • True or False?

    ADH, oestrogen and FSH are all produced by the pituitary gland.

    False.

    ADH, LH and FSH are produced by the pituitary gland. Oestrogen and progesterone are produced by the ovaries.