Syllabus Edition

First teaching 2023

First exams 2025

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Viruses (AL) (CIE A Level Biology)

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Phil

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Phil

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Biology Project Lead

Viruses

  • Viruses are microorganisms that can only be seen using an electron microscope
  • They have no cellular structure (and so are acellular) and no metabolism
  • Viruses hijack the DNA replication machinery in host cells
  • The energy viruses need for replication is provided by respiration in the host cell
  • Viruses possess none of the characteristic features used for classifying organisms so they sit outside of the three-domain classification system
  • There is a wide-ranging debate as to whether viruses should be classified as ‘living’ or ‘non-living’ based on their inability to carry out the defining features of life outside of a host cell

Classifying viruses by their genetic material

  • Viruses are classified according to the type of nucleic acid (RNA or DNA) their genome is made from, and whether it is single-stranded or double-stranded
  • In cellular organisms like animals and plants, DNA is always double-stranded and RNA is usually always single-stranded
  • However, in viruses, DNA and RNA can be either single-stranded or double-stranded
  • As a result, there are four groups of viruses that exist:
    • DNA single-stranded viruses
    • DNA double-stranded viruses
    • RNA single-stranded viruses (this is the type of genome of SARS-CoV-2, the virus responsible for the COVID-19 pandemic)
    • RNA double-stranded viruses

Diversity of Viruses Diagrams

diversity of structure in viruses

The diversity of viral structures

The coronavirus structure

Coronavirus structure

Classification of Viruses table

Nucleic acid Single or double stranded Virus Host Organism Disease
DNA Single Canine parvovirus type 2 Dog Canine parvovirus
DNA Double Varicella zoster virus (VZV) Human Chickenpox & shingles
RNA Single Morbillivirus Human Measles
RNA Double Human immunodeficiency virus Human AIDS

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Phil

Author: Phil

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.