Glycolysis (College Board AP Biology)

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Glycolysis

  • Glycolysis is the first stage of respiration
  • It takes place in the cytoplasm of the cell and involves:
    • Trapping glucose in the cell by phosphorylating the molecule
    • Splitting the glucose molecule into two
  • When 1 glucose molecule enters glycolysis, it results in the production of
    • 2 Pyruvate (3-carbon-atom) molecules
    • Net gain 2 ATP molecules - synthesized from ADP + Pi
    • 2 NADH molecules - synthesized from H+ and NAD+

Glycolysis Process Diagram

glycolysis-diagram-respiration-summarisedThe process of glycolysis

Exam Tip

It may seem strange that ATP is used and also produced during glycolysis. At the start ATP is used to make glucose more reactive (it is usually very stable) and to lower the activation energy of the reaction. Since 2 ATP are used and 4 are produced during the process, there is a net gain of 2 ATP per glucose molecule.

Memorization of the steps of glycolysis is not required

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Phil

Author: Phil

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.