Cardiac Output (AQA A Level Biology): Revision Note
Exam code: 7402
Calculating cardiac output
Cardiac output (CO) is:
the total volume of blood pumped by the heart per unit of time
The CO of an individual can be calculated using values for heart rate and stroke volume
Heart rate = number of times the heart beats per minute, or the number of cardiac cycles per minute
Stroke volume = the volume of blood pumped out of the left ventricle during one cardiac cycle
Cardiac output = heart rate x stroke volume
The equation can be rearranged to find the heart rate and stroke volume if required:
heart rate = cardiac output ÷ stroke volume
stroke volume = heart rate ÷ cardiac output
Worked Example

Step 1: find the heart rate
Three cardiac cycles occur over the course of 3 seconds
There are two sets of valve sounds per cycle
We measure a full cardiac cycle by choosing any point within the cycle and then looking at the length of time that passes before we reach the same point in the next cycle
One cardiac cycle = 1 second
The number of cardiac cycles completed in a minute, or heart rate can be calculated as follows:
60 x 1 = 60 bpm
Step 2: insert relevant figures into the equation
cardiac output = heart rate x stroke volume
= 60 x 77
= 4620 cm3
Step 3: convert into the correct units
1 dm3 = 1000 cm3
4620 ÷ 1000 = 4.62 dm3
Worked Example
An individual has a cardiac output of 4.3 dm3 and a heart rate of 72 bpm.
Calculate the individual's stroke volume. Give your answer in cm3.
Step 1: rearrange the equation
Cardiac output = heart rate x stroke volume
Stroke volume = cardiac output ÷ heart rate
Step 2: insert relevant figures into the equation
4.3 ÷ 72 = 0.0597 dm3
Step 3: convert into the correct units
1 dm3 = 1000 cm3
0.0597 x 1000 = 59.7 cm3
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