Active Transport & Co-transport (AQA A Level Biology): Revision Note

Exam code: 7402

Alistair Marjot

Written by: Alistair Marjot

Reviewed by: Ruth Brindle

Updated on

Active transport

  • Active transport is defined as:

The movement of molecules or ions through a cell membrane from a region of lower concentration to a region of higher concentration, using energy from respiration

  • Active transport requires carrier proteins (each carrier protein being specific for a particular type of molecule or ion)

  • The energy is required to make the carrier protein change shape, allowing it to transfer the molecules or ions across the cell membrane

  • Energy is provided by the hydrolysis of ATP (adenosine triphosphate) into ADP and inorganic phosphate

Diagram illustrating facilitated diffusion of polar molecules or ions through carrier proteins in a phospholipid bilayer from high to low concentration.
A carrier protein changing shape during active transport

Processes that use active transport

  • Active transport is important in:

    • Reabsorption of useful molecules and ions into the blood after filtration into the kidney tubules

    • Absorption of some products of digestion from the digestive tract

    • Loading sugar from the photosynthesising cells of leaves into the phloem tissue for transport around the plant

    • Loading inorganic ions from the soil into root hairs

Examiner Tips and Tricks

Be careful not to get carrier proteins and channel proteins confused when answering questions on active transport: active transport requires carrier proteins (transmembrane transport proteins that undergo conformational change) not channel proteins.

Co-transport

  • Co-transport is the coupled movement of two substances across a membrane via a carrier protein

  • One moves down its concentration gradient, allowing the other to move against its gradient

Processes that use co-transport

  • In the mammalian ileum, co-transport absorbs glucose and sodium ions:

    1. Active transport moves Na⁺ from the epithelial cell into the blood, creating a Na⁺ gradient.

    2. Na⁺ then diffuses in from the ileum, carrying glucose via a co-transporter.

    3. Glucose moves into the blood by facilitated diffusion

Diagram illustrating sodium and glucose transport in the intestine. Shows co-transport via sodium-glucose protein and facilitated diffusion into capillary.
Glucose molecules are absorbed by co-transport with sodium ions in the small intestine.

Examiner Tips and Tricks

Note that it can help to explain co-transport by beginning with the active part of the process (as above); this may seem a bit backwards, but active transport generates the concentration gradient needed for cotransport to occur, so this is a logical starting point

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Alistair Marjot

Author: Alistair Marjot

Expertise: Environmental Systems and Societies & Biology Content Creator

Alistair graduated from Oxford University with a degree in Biological Sciences. He has taught GCSE/IGCSE Biology, as well as Biology and Environmental Systems & Societies for the International Baccalaureate Diploma Programme. While teaching in Oxford, Alistair completed his MA Education as Head of Department for Environmental Systems & Societies. Alistair has continued to pursue his interests in ecology and environmental science, recently gaining an MSc in Wildlife Biology & Conservation with Edinburgh Napier University.

Ruth Brindle

Reviewer: Ruth Brindle

Expertise: Biology Content Creator

Ruth graduated from Sheffield University with a degree in Biology and went on to teach Science in London whilst also completing an MA in innovation in Education. With 10 years of teaching experience across the 3 key science disciplines, Ruth decided to set up a tutoring business to support students in her local area. Ruth has worked with several exam boards and loves to use her experience to produce educational materials which make the mark schemes accessible to all students.