Active Transport & Co-transport (AQA A Level Biology): Revision Note
Exam code: 7402
Active transport
Active transport is defined as:
The movement of molecules or ions through a cell membrane from a region of lower concentration to a region of higher concentration, using energy from respiration
Active transport requires carrier proteins (each carrier protein being specific for a particular type of molecule or ion)
The energy is required to make the carrier protein change shape, allowing it to transfer the molecules or ions across the cell membrane
Energy is provided by the hydrolysis of ATP (adenosine triphosphate) into ADP and inorganic phosphate

Processes that use active transport
Active transport is important in:
Reabsorption of useful molecules and ions into the blood after filtration into the kidney tubules
Absorption of some products of digestion from the digestive tract
Loading sugar from the photosynthesising cells of leaves into the phloem tissue for transport around the plant
Loading inorganic ions from the soil into root hairs
Examiner Tips and Tricks
Be careful not to get carrier proteins and channel proteins confused when answering questions on active transport: active transport requires carrier proteins (transmembrane transport proteins that undergo conformational change) not channel proteins.
Co-transport
Co-transport is the coupled movement of two substances across a membrane via a carrier protein
One moves down its concentration gradient, allowing the other to move against its gradient
Processes that use co-transport
In the mammalian ileum, co-transport absorbs glucose and sodium ions:
Active transport moves Na⁺ from the epithelial cell into the blood, creating a Na⁺ gradient.
Na⁺ then diffuses in from the ileum, carrying glucose via a co-transporter.
Glucose moves into the blood by facilitated diffusion

Examiner Tips and Tricks
Note that it can help to explain co-transport by beginning with the active part of the process (as above); this may seem a bit backwards, but active transport generates the concentration gradient needed for cotransport to occur, so this is a logical starting point
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