The Autonomic Nervous System (AQA A Level Biology): Revision Note

Exam code: 7402

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Naomi Holyoak

Updated on

Control of heart rate

  • While the initiation of the heartbeat is myogenic, there are times when heart rate needs to change from its baseline rate

    • E.g. during exercise

The autonomic nervous system

  • Heart rate is controlled by the cardioregulatory centre in the medulla of the brain, which is connected to the sinoatrial node (SAN) by nerves of the autonomic nervous system

  • The autonomic nervous system controls unconscious activities, such as heart rate, breathing rate and digestion; it has two branches:

    • the sympathetic branch is involved with 'fight or flight', e.g.:

      • increasing heart rate

      • increasing breathing rate

      • diverting blood flow to muscles

    • the parasympathetic branch is involved with 'rest and digest', e.g.:

      • slowing heart rate

      • slowing breathing rate

      • digesting food

Location of medulla. (1), downloadable AS & A Level Biology revision notes
Location of medulla. (2), downloadable AS & A Level Biology revision notes
The SAN receives stimulation from either the sympathetic or parasympathetic branch of the the autonomic nervous system

Chemoreceptors and pressure receptors

  • Whether the medulla sends nerve impulses via a sympathetic or parasympathetic nerve depends on information from receptors in the blood vessels, e.g.:

    • chemoreceptors detect the carbon dioxide concentration of the blood

      • CO2 concentration affects blood pH, which is also detected by chemoreceptors

    • pressure receptors detect blood pressure

Stimulus and receptors

Changes in nervous system

Heart rate

Low blood CO2 detected by chemoreceptors

High blood pressure detected by pressure receptors

  1. Impulses sent along sensory neurones to medulla

  2. Impulses sent along parasympathetic neurones to the SAN

  3. Acetylcholine released, which binds to receptors on SAN

  4. SAN decreases frequency of heart beat initiation

Decreases

High blood CO2 detected by chemoreceptors

Low blood pressure detected by pressure receptors

  1. Impulses sent along sensory neurones to medulla

  2. Impulses sent along sympathetic neurones to the SAN

  3. Noradrenaline released, which binds to receptors on SAN

  4. SAN increases frequency of heart beat initiation

Increases

Flowchart illustrating the response of heart rate to changes in blood CO2, detailing stimuli, receptors, coordinator, effectors, and response.
Impulses reaching the SAN via the sympathetic nervous system result in release of noradrenaline and an increased heart rate, while impulses arriving via the parasympathetic nervous system result in release of acetylcholine and a decreased heart rate

Examiner Tips and Tricks

Be careful not to confuse the roles of the SAN and the autonomic nervous system here:

  • The SAN initiates the heart beat

  • It can change its rate of initiation in response to stimulation from the autonomic nervous system

Investigating factors affecting heart rate

  • It is possible to investigate the effect of a named variable on an organism's heart rate, e.g. the effect of:

    • caffeine

    • alcohol

    • temperature

    • diet

    • dehydration

Investigating the effect of caffeine on heart rate in humans

Apparatus

  • Heart rate monitor, or stopwatch

  • Drinking water and caffeinated drink, e.g. cola, energy drink or coffee

  • Measuring cylinders

  • Cups

  • Volunteers, with no heart conditions or caffeine sensitivity

Method

  1. Divide volunteers into two groups

  2. Measure resting heart rate for both groups by sitting quietly for 5 minutes before recording heart rate, e.g. by:

    • using a heart rate monitor

    • counting beats at the wrist for 30 seconds, then multiply by 2 to get beats per minute

  3. Use the measuring cylinder to pour 200ml of a caffeine drink or water into a cup

  4. Ask each individual to consume the drink

    • Group 1: caffeine drink

    • Group 2 (control group): the same volume of water

  5. Wait 15 minutes

    • All volunteers should be resting during this time, and should not consume any other food or drink

  6. Record the heart rates of each individual again

  7. Repeat the heart rate measurements every 15 minutes for 2 hours

    • This will show the duration for which caffeine has an effect on the heart rate

  8. Process the data, e.g.:

    • calculate the mean heart rate of each group

    • present the results in a graph form

    • calculate cardiac output

Limitations

  • It is very difficult to ensure that variables other than caffeine consumption are controlled during this type of experiment, e.g. there may be differences between individuals such as:

    • different food consumed prior to experiment

    • different fitness levels

    • different responses to caffeine

    • taking part in the experiment may have unpredictable effects on heart rate

  • Using a large enough group of volunteers should help to reduce the problem described above, but this can be difficult in a school setting

Examiner Tips and Tricks

When writing designs for experiments like this one, you should always consider factors such as:

  • how control variables will be controlled

  • the importance of a control group (and how this differs from control variables)

  • how the results will be analysed, e.g. type of graph, appropriate statistical tests

  • sample size and repeats

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology, Psychology & Sociology Subject Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Naomi Holyoak

Reviewer: Naomi Holyoak

Expertise: Biology Content Creator

Naomi graduated from the University of Oxford with a degree in Biological Sciences. She has 8 years of classroom experience teaching Key Stage 3 up to A-Level biology, and is currently a tutor and A-Level examiner. Naomi especially enjoys creating resources that enable students to build a solid understanding of subject content, while also connecting their knowledge with biology’s exciting, real-world applications.