The Effects of Lung Disease (AQA A Level Biology): Revision Note

Exam code: 7402

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Naomi Holyoak

Updated on

The effects of lung disease

  • There are several conditions that can reduce lung function, e.g. by affecting the structure of the alveolar walls and/or damaging the airways

  • Examples of lung diseases that affect gas exchange include:

    • lung cancer

      • Tumours develop in the lungs due to uncontrolled cell division

      • The tumour may interfere with the normal working of the lungs, e.g. by squeezing against blood vessels or blocking airways

    • COPD

      • Chronic obstructive pulmonary disease (COPD) includes a range of conditions, such as chronic bronchitis and emphysema

      • COPD causes damage to the lungs or airways, reducing air flow and/or the rate of gas exchange

Examiner Tips and Tricks

Note that you are not required to learn details of different types of lung disease; an exam question will provide any relevant information about a lung disease and expect you to apply your knowledge of the gas exchange system to explain disease symptoms.

Worked Example

The image below compares the alveoli tissue of a healthy individual with that of of a patient with emphysema. Patients with emphysema suffer from symptoms such as shortness of breath and fatigue.

Comparison of lung tissue: left side shows normal structure with dense, intricate patterns; right side shows emphysema with larger, less dense spaces.

With reference to the image provided, explain the symptoms of emphysema patients.

[3]

Answer:

  • Emphysema patients have fewer alveoli / larger alveoli SO they have a reduced lung surface area; [1 mark]

  • The rate of diffusion taking place will be reduced SO less oxygen will enter the blood (causing breathlessness); [1 mark]

  • There will be a reduced rate of respiration SO less energy will be released (causing fatigue); [1 mark]

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology, Psychology & Sociology Subject Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Naomi Holyoak

Reviewer: Naomi Holyoak

Expertise: Biology Content Creator

Naomi graduated from the University of Oxford with a degree in Biological Sciences. She has 8 years of classroom experience teaching Key Stage 3 up to A-Level biology, and is currently a tutor and A-Level examiner. Naomi especially enjoys creating resources that enable students to build a solid understanding of subject content, while also connecting their knowledge with biology’s exciting, real-world applications.