Binary Fission (AQA AS Biology): Revision Note
Exam code: 7401
Binary fission of prokaryotic cells
Cell division in prokaryotes is called binary fission
It is simpler than mitosis as cells have no nucleus, chromosomes, spindle fibres, or membrane-bound organelles
Prokaryotes only need to replicate
a single, circular DNA molecule
plasmids: small, circular DNA molecules
The process of binary fission
The circular DNA molecule is replicated
Plasmids replicate
The cytoplasm divides (roughly) equally between daughter cells
Each daughter cell is genetically identical and receives
one copy of circular DNA
a variable number of plasmids
There are mechanisms to ensure that all daughter cells inherit a copy of the single, circular DNA molecule along with some plasmids
If a daughter cell does not receive the single circular DNA molecule or at least one copy of a plasmid, it dies

Examiner Tips and Tricks
Binary fission can be a rapid process. Bacteria can divide every 20 minutes under ideal conditions. This rapid reproduction allows them to:
Colonise new environments quickly
Outcompete other microbes
Accumulate mutations faster, increasing genetic variation (contributing to the issues surrounding antibiotic resistance)
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