Structured Questions (AS Only) (AQA AS Biology): Exam Questions

Exam code: 7401

26 mins2 questions
1a3 marks

Figure 1 represents part of the gas exchange system of an insect.

Figure 1

Diagram showing a cross-section of body tissue. Label A indicates outer body, B marks a tubular structure, and C shows branching connections inside the tissue.

(i) Name the part labelled A in Figure 1.

[1]

(ii) Describe the role of A in insect gas exchange.

[2]

1b4 marks

Identify and explain two features of the insect gas exchange system that maximise the rate of oxygen uptake.

1c3 marks

Insects have an open circulatory system in which a blood-like fluid, called haemolymph, flows freely through the body cavity. A tubular heart located along the back of the insect pumps haemolymph forward in waves. The fluid is released into spaces surrounding the organs, where it directly bathes the tissues. Haemolymph is responsible for transporting nutrients, hormones, and waste products, and for helping to regulate internal conditions.

Explain how the circulatory system of a human differs to that of an insect.

1d3 marks

In very active insects the muscles produce lactate during anaerobic respiration, which drives the movement of water out of the tracheoles and into the muscle cells.

Suggest how lactate production helps to maintain a high rate of oxygen diffusion into muscle cells.

2a1 mark

CRISPR-Cas9 is a gene-editing technology that uses an enzyme called Cas9, to cut DNA at a specific point, allowing genes to be removed, added, or altered within an organism's genome.

Define the term genome.

2b3 marks

Scientists have used CRISPR-Cas9 gene editing to successfully remove HIV DNA from infected human cells in laboratory settings.

Describe how HIV DNA becomes incorporated into human DNA after infection.

2c6 marks

Once HIV DNA is integrated into the host genome, it can be used to produce viral proteins.

2d2 marks

HIV produces long polyproteins that must be cut into smaller sections in order to assemble the capsid and enzymes in new viral particles.

Suggest how antiretroviral treatments (ARTs) that contain a protease inhibitor might prevent new viral particles from assembling.

2e1 mark

Suggest one reason why CRISPR-Cas9 provides a better treatment for people with HIV than ART.