Blood Glucose Regulation (SQA National 5 Biology): Revision Note
Exam code: X807 75
Blood glucose regulation
Blood glucose concentration is monitored and controlled by the pancreas, which acts as an endocrine gland (secreting hormones into the bloodstream)
Maintaining blood glucose within a narrow range is vital for normal body function
Eating carbohydrate-rich foods increases glucose levels in the bloodstream
If blood glucose concentration gets too high:
Cells in the pancreas detect the rise
The pancreas secretes insulin into the blood
Insulin stimulates muscle and liver cells to absorb glucose and store it as glycogen (an insoluble storage form of glucose)
This lowers blood glucose concentration back to normal, and the pancreas stops releasing insulin
If blood glucose concentration gets too low:
Cells in the pancreas detect the drop
The pancreas secretes glucagon into the blood
Glucagon stimulates the liver to break down glycogen into glucose and release it into the bloodstream
This raises blood glucose concentration back to normal, and the pancreas stops releasing glucagon

Examiner Tips and Tricks
Summary of key roles:
Insulin – Lowers blood glucose by converting glucose to glycogen
Glucagon – Raises blood glucose by converting glycogen to glucose
Glycogen – Storage form of glucose in the liver and muscles
Pancreas – Monitors glucose levels and secretes insulin and glucagon
Liver – Stores glycogen and releases glucose when needed
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