Blood Glucose Regulation (SQA National 5 Biology): Revision Note

Exam code: X807 75

Ruth Brindle

Last updated

Blood glucose regulation

  • Blood glucose concentration is monitored and controlled by the pancreas, which acts as an endocrine gland (secreting hormones into the bloodstream)

  • Maintaining blood glucose within a narrow range is vital for normal body function

  • Eating carbohydrate-rich foods increases glucose levels in the bloodstream

    • If blood glucose concentration gets too high:

      • Cells in the pancreas detect the rise

      • The pancreas secretes insulin into the blood

      • Insulin stimulates muscle and liver cells to absorb glucose and store it as glycogen (an insoluble storage form of glucose)

      • This lowers blood glucose concentration back to normal, and the pancreas stops releasing insulin

    • If blood glucose concentration gets too low:

      • Cells in the pancreas detect the drop

      • The pancreas secretes glucagon into the blood

      • Glucagon stimulates the liver to break down glycogen into glucose and release it into the bloodstream

      • This raises blood glucose concentration back to normal, and the pancreas stops releasing glucagon

Flowchart of blood glucose regulation, including insulin and glucagon actions, illustrating rises and falls in glucose levels and involvement of adrenaline.
Insulin and glucagon are responsible for glucose regulation in the human body

Examiner Tips and Tricks

Summary of key roles:

  • Insulin – Lowers blood glucose by converting glucose to glycogen

  • Glucagon – Raises blood glucose by converting glycogen to glucose

  • Glycogen – Storage form of glucose in the liver and muscles

  • Pancreas – Monitors glucose levels and secretes insulin and glucagon

  • Liver – Stores glycogen and releases glucose when needed

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Ruth Brindle

Author: Ruth Brindle

Expertise: Biology Content Creator

Ruth graduated from Sheffield University with a degree in Biology and went on to teach Science in London whilst also completing an MA in innovation in Education. With 10 years of teaching experience across the 3 key science disciplines, Ruth decided to set up a tutoring business to support students in her local area. Ruth has worked with several exam boards and loves to use her experience to produce educational materials which make the mark schemes accessible to all students.