Extended Response (AS Only) (AQA AS Biology): Exam Questions

Exam code: 7401

2 hours12 questions
1a
5 marks

DNA replication must be very accurate to ensure normal growth and development of organisms. Describe and explain how the structure of DNA results in a high level of accuracy during replication.

1b
5 marks

DNA replication is part of the process of cell replication during mitosis. Describe how chromosomes behave during mitosis and explain how two genetically identical cells are produced as a result of this.

2a
5 marks

When food passes to the small intestine, starch molecules are broken down to maltose by pancreatic amylase. This process takes place at normal body temperature.

Explain why amylase only breaks down starch and why amylase allows this reaction to take place at normal body temperature.

2b
5 marks

Once amylase has broken starch down into maltose, maltase can then break maltose down into glucose.

Describe how glucose is then absorbed so it can be used by the body.

3a
5 marks

Some white blood cells are known as phagocytes.

Describe how these cells destroy bacteria.

3b
5 marks

A biologist wanted to view the cell structure of a phagocyte using a transmission electron microscope (TEM).

Explain the possible limitations of using a TEM to do this.

4a
5 marks

Starch and cellulose are both polysaccharides made up of many glucose molecules.
However, they both have different structures and functions. Describe and explain how the structures of starch and cellulose molecules relate to their functions.

4b
5 marks

Amylase is an enzyme that can break down starch into maltose. Biologists have investigated how competitive and non-competitive inhibitors affect amylase.

Describe competitive and non-competitive inhibition of enzymes.

5a
5 marks

Describe the production of mRNA in an animal cell.

5b
5 marks

The mRNA in part (b) can now be used to form a polypeptide via a process known as translation.

Describe how this occurs.

6a
5 marks

Plants have to transport substances, such as water and sugars, along their stems. The cohesion-tension theory explains how water is transported in the xylem. Describe this theory.

6b
5 marks

Describe how sugars are transported in plant stems.

7a
5 marks

Cell fractionation and ultracentrifugation are techniques that can be used to isolate organelles from a suspension of cells. Describe and explain how these techniques can be used to isolate mitochondria from animal cells.

7b
5 marks

The mitochondria in part (a) contain their own DNA. Give similarities and differences (stating at least two of each) between the DNA in a eukaryotic cell and the DNA in a prokaryotic cell.

8a
5 marks

Contrast active and passive immunity.

8b
5 marks

Vaccines designed to protect people from Covid-19 are currently being developed by many different scientific research laboratories around the world.

Explain how vaccines can protect humans from disease-causing organisms.

9a
5 marks

Sodium ions and oxygen are two substances that are able to diffuse across cell-surface membranes. The diffusion of Sodium ions requires a membrane protein, whereas the diffusion of oxygen does not

Explain why.

9b
5 marks

The fact that oxygen can diffuse across cell-surface membranes allows us to respire.
Our lungs have many adaptations to ensure the fast exchange of oxygen between air in the alveoli and blood in the capillaries around them.

Describe and explain these adaptations.

10a
5 marks

The process of meiosis begins with the chromosomes condensing. Describe what happens to the chromosomes next.

10b
5 marks

Meiosis results in genetic variation in gametes. This leads to variation in the offspring formed by sexual reproduction. Explain why this variation is advantageous for a species.

11a
4 marks

Microorganisms may secrete cellulase enzymes to break down cellulose in dead plant material.

Explain why cellulase only breaks down cellulose.

11b
6 marks

Environmental scientists have investigated how competitive and non-competitive inhibitors affect cellulase activity in soil ecosystems.

Describe competitive and non-competitive inhibition of enzymes.

12a
4 marks

Mucus, produced by epithelial cells in the human gas exchange system, contains glycoproteins. One of the glycoproteins is a modified polypeptide that has the sugar lactose attached to it.

Describe how the sugar lactose is formed, and state the location within the cell where the polypeptide is attached to lactose to form a glycoprotein.

12b
6 marks

Describe the anatomy of the human gas exchange system and the mechanism of inhalation and exhalation.