Mutations (SQA National 5 Biology): Revision Note

Exam code: X807 75

Naomi Holyoak

Last updated

The definition of mutation

  • A mutation is a random change to the genetic material

    • Mutations are said to be random because they occur spontaneously, meaning that they do not need to be triggered by external factors in the environment

  • While mutations occur randomly, environmental factors, such as radiation and some chemicals, can increase the rate at which they occur

  • New alleles may arise due to mutation, and these alleles may affect the features of organisms

    • Mutation is the only source of new alleles, though alleles may be recombined in different ways by other processes

  • Mutations may be:

    • neutral: these have no impact on survival

    • advantageous: these increase the chances of survival

    • disadvantageous: these decrease the chances of survival

Diagram of a DNA strand showing variation; most have guanine, some have thymine. Two human figures indicate population context.
One example of a mutation is a change in a single base within the DNA sequence; here guanine is swapped for thymine

New alleles & variation

  • The new alleles produced by mutation can result in some plants and animals becoming better adapted to their environment

    • This occurs when advantageous mutations increase survival chances

  • Different mutations will occur in different individuals, introducing variation into a population

  • Variation within a population makes it possible for a population to evolve, or change, over time in response to changing environmental conditions

Examiner Tips and Tricks

Be careful with the language that you use when describing the ideas discussed here. Remember that:

  • mutations occur at random, not in direct response to changes in the environment

  • when random mutations result in a survival advantage, they allow a population as a whole to respond to a changing environment

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Naomi Holyoak

Author: Naomi Holyoak

Expertise: Biology Content Creator

Naomi graduated from the University of Oxford with a degree in Biological Sciences. She has 8 years of classroom experience teaching Key Stage 3 up to A-Level biology, and is currently a tutor and A-Level examiner. Naomi especially enjoys creating resources that enable students to build a solid understanding of subject content, while also connecting their knowledge with biology’s exciting, real-world applications.