Meiosis in Animal & Plant cells (AQA A Level Biology): Revision Note

Exam code: 7402

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Cara Head

Updated on

Meiosis in animal & plant cells

  • Meiosis is a form of nuclear division that results in the production of haploid cells from diploid cells

  • It produces gametes in plants and animals that are used in sexual reproduction

  • It has many similarities to mitosis however, it has two divisions: meiosis I and meiosis II

  • Within each division, there are the following stages: prophase, metaphase, anaphase and telophase

Meiosis I

  • Meiosis I is the first division in meiosis

  • It separates homologous chromosomes and reduces the chromosome number by half, producing two haploid cells

Prophase I

  • DNA replication has already occurred

  • DNA condenses and becomes visible as chromosomes

  • The chromosomes are arranged side by side in homologous pairs

  • Crossing over of non-sister chromatids may occur

  • The spindle is formed by centrioles

  • The nuclear envelope breaks down, and the nucleolus disintegrates

Metaphase I

  • Homologous pairs of chromosomes line up randomly along the equator of the spindle

  • Independent segregation occurs in metaphase I

Anaphase I

  • The homologous pairs of chromosomes are separated as microtubules pull whole chromosomes to opposite ends of the spindle

    • The centromeres do not divide

Telophase I

  • The chromosomes arrive at opposite poles

  • Spindle fibres start to break down

  • Nuclear envelopes form around the two groups of chromosomes, and nucleoli reform

  • The cell then divides by cytokinesis, forming two haploid daughter cells — each with half the original chromosome number (but still with duplicated chromosomes)

    • These cells are haploid as they contain half the number of centromeres

Meiosis I stages (1), downloadable AS & A Level Biology revision notes
Diagram of anaphase and telophase in cell division, showing chromosomes moving to spindle poles, cytokinesis, and reformation of the nuclear envelope.
The stages of meiosis I

Meiosis II

  • There is no interphase between meiosis I and meiosis II, so the DNA is not replicated

  • The second division of meiosis is almost identical to the stages of mitosis

Prophase II

  • The nuclear envelope breaks down and chromosomes condense

  • A spindle forms at a right angle to the old one

Metaphase II

  • Chromosomes (still made of two sister chromatids) line up in a single file along the equator of the spindle

Anaphase II

  • Centromeres divide, and individual chromatids are pulled to opposite poles

    • Each chromatid is now an individual chromosome

  • This creates four groups of chromosomes that have half the number of chromosomes compared to the original parent cell

Telophase II

  • Nuclear membranes form around each group of chromosomes

  • Cytokinesis occurs

    • Cytoplasm divides as new cell surface membranes are formed, creating four haploid cells

 

Meiosis II PMA, downloadable AS & A Level Biology revision notes

 

Diagram of telophase II in meiosis, showing cytokinesis and formation of four haploid daughter cells with reforming nuclear membranes.
The stages of meiosis II

Examiner Tips and Tricks

Understanding the difference between chromosomes and chromatids can be tricky. Chromosomes are counted by centromeres—so even after DNA replication in interphase, the number of chromosomes stays at 46 because there are still 46 centromeres. However, each chromosome now consists of two sister chromatids, making a total of 92 chromatids.

You need to be able to complete diagrams showing the chromosome content of cells after the first and second meiotic divisions, when given the chromosome content of the parent cell.

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology, Psychology & Sociology Subject Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Cara Head

Reviewer: Cara Head

Expertise: Biology & Psychology Content Creator

Cara graduated from the University of Exeter in 2005 with a degree in Biological Sciences. She has fifteen years of experience teaching the Sciences at KS3 to KS5, and Psychology at A-Level. Cara has taught in a range of secondary schools across the South West of England before joining the team at SME. Cara is passionate about Biology and creating resources that bring the subject alive and deepen students' understanding

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