Inorganic Ions (AQA A Level Biology): Revision Note

Exam code: 7402

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Cara Head

Updated on

Inorganic ions

  • An ion is an atom (or sometimes a group of atoms) that has an electrical charge

    • An ion that has a positive charge is known as a cation

    • An ion that has a negative charge is known as an anion

  • An inorganic ion is an ion that does not contain carbon

  • Inorganic ions occur in solution in the cytoplasm and body fluids of organisms

    • The concentration of certain ions can fluctuate and can be used in cell signalling and neuronal transmission

Properties & roles of inorganic ions

Hydrogen ions

  • Hydrogen ions (H+) are protons

  • The concentration of H+ in a solution determines the pH

  • There is an inverse relationship between the pH value and the hydrogen ion concentration

    • The more H+ ions present, the lower the pH (the more acidic the solution)

    • The fewer H+ ions present, the higher the pH (the more alkaline the solution)

  • The concentration of H+ is therefore very important for enzyme-controlled reactions, which are all affected by pH

    • The fluids in the body normally have a pH value of approximately 7.4

    • The maintenance of this normal pH is essential for many of the metabolic processes that take place within cells

    • Changes in pH can affect enzyme structure

Iron ions

  • There are two versions of iron ions (known as oxidation states)

    • Iron (II) ions, also known as ferrous ions (Fe2+)

    • Iron (III) ions, also known as ferric ions (Fe3+)

  • Iron ions are essential as they can bind oxygen

    • Haemoglobin is the large protein in red blood cells that is responsible for transporting oxygen around the body

    • Haemoglobin is made up of four polypeptide chains that each contain one Fe2+

    • This Fe2+ is a key component in haemoglobin as it binds to oxygen

Sodium ions

  • Sodium ions (Na+) are required for the transport of glucose and amino acids across cell-surface membranes (e.g. in the small intestine)

    • Glucose and amino acid molecules can only enter cells (through carrier proteins) alongside Na+ in a process known as co-transport

  • Na+ is also required for the transmission of nerve impulses

Phosphate ions

  • Phosphate ions (PO43-) attach to other molecules to form phosphate groups, which are an essential component of DNA, RNA and ATP

  • In DNA and RNA, the phosphate groups allow individual nucleotides tobond to form polynucleotides

  • In ATP, the bonds between phosphate groups store energy

    • These phosphate groups can be easily attached or detached

    • When the bonds between phosphate groups are broken, they release a large amount of energy, which can be used for cellular processes

  • Phosphates are also found in phospholipids, which are key components of the phospholipid bilayer of cell membranes

Examiner Tips and Tricks

You should know the following inorganic ions, as well as their properties and roles in the body:

  • Hydrogen ions (H+) and pH

  • Iron ions (Fe2+/Fe3+) as a component of haemoglobin

  • Sodium ions (Na+) in the co-transport of glucose and amino acids

  • Phosphate ions (PO43-) as components of DNA and of ATP

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology, Psychology & Sociology Subject Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Cara Head

Reviewer: Cara Head

Expertise: Biology & Psychology Content Creator

Cara graduated from the University of Exeter in 2005 with a degree in Biological Sciences. She has fifteen years of experience teaching the Sciences at KS3 to KS5, and Psychology at A-Level. Cara has taught in a range of secondary schools across the South West of England before joining the team at SME. Cara is passionate about Biology and creating resources that bring the subject alive and deepen students' understanding