Active Transport & Co-transport (AQA AS Biology): Revision Note
Exam code: 7401
Active transport
- Active transport is defined as: 
The movement of molecules or ions through a cell membrane from a region of lower concentration to a region of higher concentration, using energy from respiration
- Active transport requires carrier proteins (each carrier protein being specific for a particular type of molecule or ion) 
- The energy is required to make the carrier protein change shape, allowing it to transfer the molecules or ions across the cell membrane 
- Energy is provided by the hydrolysis of ATP (adenosine triphosphate) into ADP and inorganic phosphate 

Processes that use active transport
- Active transport is important in: - Reabsorption of useful molecules and ions into the blood after filtration into the kidney tubules 
- Absorption of some products of digestion from the digestive tract 
- Loading sugar from the photosynthesising cells of leaves into the phloem tissue for transport around the plant 
- Loading inorganic ions from the soil into root hairs 
 
Examiner Tips and Tricks
Be careful not to get carrier proteins and channel proteins confused when answering questions on active transport: active transport requires carrier proteins (transmembrane transport proteins that undergo conformational change) not channel proteins.
Co-transport
- Co-transport is the coupled movement of two substances across a membrane via a carrier protein 
- One moves down its concentration gradient, allowing the other to move against its gradient 
Processes that use co-transport
- In the mammalian ileum, co-transport absorbs glucose and sodium ions: - Active transport moves Na⁺ from the epithelial cell into the blood, creating a Na⁺ gradient. 
- Na⁺ then diffuses in from the ileum, carrying glucose via a co-transporter. 
- Glucose moves into the blood by facilitated diffusion (opens in a new tab) 
 

Examiner Tips and Tricks
Note that it can help to explain co-transport by beginning with the active part of the process (as above); this may seem a bit backwards, but active transport generates the concentration gradient needed for cotransport to occur, so this is a logical starting point
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