Ventilation & Gas Exchange (AQA AS Biology): Revision Note

Exam code: 7401

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Naomi Holyoak

Updated on

Ventilation & gas exchange

  • Gas exchange in the lungs occurs when:

    • oxygen diffuses down its concentration gradient from the air into the blood

    • carbon dioxide diffuses down its concentration gradient from the blood into the air

  • The concentration gradients required for effective gas exchange are maintained by:

    • ventilation in the lungs

    • the continuous flow of blood in the capillaries

Ventilation

  • Ventilation is the process of moving air in and out of the lungs; this involves:

    • breathing in, or inhalation

    • breathing out, or exhalation

Examiner Tips and Tricks

Be careful not to confuse ventilation and respiration: ventilation is breathing in and out, while respiration is a chemical reaction that releases chemical energy from biological molecules

Breathing in

  • The mechanism by which air is drawn into the lungs is as follows:

    1. The diaphragm contracts and flattens and the external intercostal muscles contract

    2. The ribcage moves upwards and outwards

    3. Chest volume increases, resulting in a pressure decrease

    4. Air moves into the lungs down a pressure gradient

  • The process of breathing out is active; it requires energy for muscle contraction

Diagram of inhalation showing air drawn into the lungs. External intercostal muscles expand the ribcage, diaphragm contracts, increasing thorax volume.
Inhalation is an active process, during which the external intercostal muscles and diaphragm contract

Breathing out

  • The mechanism by which air is forced out of the lungs is as follows:

    1. The diaphragm relaxes and curves upwards and the external intercostal muscles relax

    2. The ribcage moves downwards and inwards

    3. Chest volume decreases, resulting in a pressure increase

    4. Air moves out of the lungs down a pressure gradient

  • When at rest breathing out is a passive process that occurs due to the elastic recoil of the lung tissue

Diagram illustrating human exhalation, showing diaphragm relaxation, ribcage movement, and air being expelled from lungs with descriptive labels.
Normal exhalation is a passive process, during which the diaphragm and external intercostal muscles relax
  • During forced exhalation the process can become active:

    • Internal intercostal muscles contract to pull the ribs down and the abdominal muscles contract to push organs upwards against the diaphragm

    • These actions decrease the chest volume further, increasing the pressure and forcing more air out of the lungs

Examiner Tips and Tricks

The intercostal muscles work against each other in an antagonistic manner; as one contracts, the other relaxes.

Calculating pulmonary ventilation rate

  • The volume of air breathed by an individual over a minute is known as the pulmonary ventilation rate (PVR); it is determined by:

    • breathing rate: the number of breaths per minute

    • tidal volume: volume of air breathed in per normal breath

  • PVR can be calculated as follows:

PVR = tidal volume x breathing rate

Worked Example

An individual's pulmonary ventilation rate at rest was found to be 7.4 dm3 min-1. They took 12 breaths in one minute.

Calculate the individual's tidal volume.

Step one: rearrange the equation

  • PVR = tidal volume x breathing rate

  • Rearrange to:

tidal volume = PVR ÷ breathing rate

Step two: insert relevant values into equation

tidal volume = 7.4 ÷ 12

= 0.6166

tidal volume = 0.62 dm3

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology, Psychology & Sociology Subject Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Naomi Holyoak

Reviewer: Naomi Holyoak

Expertise: Biology Content Creator

Naomi graduated from the University of Oxford with a degree in Biological Sciences. She has 8 years of classroom experience teaching Key Stage 3 up to A-Level biology, and is currently a tutor and A-Level examiner. Naomi especially enjoys creating resources that enable students to build a solid understanding of subject content, while also connecting their knowledge with biology’s exciting, real-world applications.

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