Meiosis (AQA AS Biology): Revision Note

Exam code: 7401

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Cara Head

Updated on

Meiosis

  • Meiosis produces daughter cells that are genetically different from each other and to the parent cell

  • This is due to the processes of independent segregation and crossing over

Independent segregation

  • The independent segregation of homologous chromosomes leads to genetically different daughter cells

  • This happens during meiosis:

    • Meiosis is the process that forms gametes (sperm or egg), and it has two divisions: meiosis I and meiosis II

  • During meiosis I, homologous chromosomes line up in the centre of the cell

  • The chromosomes are then separated and pulled into different cells — this is called segregation of homologous chromosomes

  • Each pair of homologous chromosomes lines up randomly

    • That means the way one pair segregates does not affect how another pair segregates

    • This is what makes it independent — each chromosome pair has its a different path by chance

Diagram illustrating meiosis: two pairs of homologous chromosomes, two possible orientations, and four resulting gametes from meiosis II.
Independent segregation in meiosis

Examiner Tips and Tricks

The AQA specification refers to independent segregation, but you may also see the term independent assortment. Use the phrase "independent segregation of homologous chromosomes" to stick to specification language. 'Independent assortment' will often be accepted in explanations in your answers, but 'independent segregation' is more precise for AQA.

Crossing over

  • Crossing over is the process where homologous chromosomes exchange genetic material during meiosis I

  • This process results in further genetic variation among daughter cells

  • Homologous chromosomes pair up and form bivalents

  • The chromatid then breaks and rejoins to the chromatid of its homologous chromosome, so that its alleles are exchanged

  • Crossing over leads to new combinations of alleles on each chromatid; this is called recombination

Diagram illustrating genetic crossing over. Shows homologous chromosomes exchanging genetic material at chiasma, producing recombinant chromatids.
Crossing over occurs during meiosis I

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology, Psychology & Sociology Subject Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Cara Head

Reviewer: Cara Head

Expertise: Biology & Psychology Content Creator

Cara graduated from the University of Exeter in 2005 with a degree in Biological Sciences. She has fifteen years of experience teaching the Sciences at KS3 to KS5, and Psychology at A-Level. Cara has taught in a range of secondary schools across the South West of England before joining the team at SME. Cara is passionate about Biology and creating resources that bring the subject alive and deepen students' understanding

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