Aerobic & Anaerobic Respiration (Edexcel IGCSE Biology): Revision Note
Exam code: 4BI1
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Aerobic Respiration
Aerobic respiration requires oxygen and takes place in the mitochondria in the cell
It is defined as the chemical process in cells that uses oxygen to break down nutrient molecules to release energy in the form of ATP
Aerobic respiration is the complete breakdown of glucose to release a relatively large amount of energy in the form of ATP for use in cellular processes and reactions.
Carbon dioxide and water are also produced as waste products
Word equation for aerobic respiration

Symbol equation for aerobic respiration
This equation can also be shown as a balanced chemical equation
One molecule of glucose reacts with six molecules of oxygen to produce six molecules of carbon dioxide and six molecules of water

Examiner Tips and Tricks
You need to know both the word equation and the balanced chemical symbol equation for aerobic respiration in living organisms. If an exam question asks you to give the balanced symbol equation for respiration, then you must write out the symbol equation and it will need to be balanced for full marks. If you give the word equation when asked for the balanced symbol equation, you will not be given credit.
Always check what the question is asking you for!
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Anaerobic Respiration
Anaerobic respiration does not require oxygen
It is defined as the chemical process in cells that breaks down nutrient molecules to release energy without using oxygen
It involves the incomplete breakdown of glucose and so releases a a smaller amount of energy in the form of ATP than aerobic respiration
Different waste products are formed depending on the type of organism that the anaerobic respiration is taking place in
Anaerobic respiration in animals
Anaerobic respiration mainly takes place in muscle cells during vigorous exercise
When we exercise at high intensities, our muscles have a higher demand for energy
Our bodies can only deliver so much oxygen to our muscle cells for aerobic respiration
When oxygen supply is insufficient, some glucose is broken down without it anaerobically, producing lactic acid instead
Glucose has not been fully broken down meaning there is still energy stored within the bonds of lactic acid molecules
Lactic acid builds up in muscle cells and lowers the pH of the muscle tissue (making the conditions more acidic)
Acidic conditions can denature the enzymes in cells
Lactic acid will eventually be broken down using oxygen to produce carbon dioxide and water as waste products
Anaerobic respiration releases less energy than aerobic respiration

Anaerobic respiration in plants and fungi
Plants and yeast can respire without oxygen as well, breaking down glucose in the absence of oxygen to produce ethanol and carbon dioxide
Anaerobic respiration in yeast cells is called fermentation
Fermentation is economically important in the manufacture of bread (where the carbon dioxide produced helps the dough to rise)

Examiner Tips and Tricks
You need to know the word equations for anaerobic respiration in animals and plants (or fungi) but not the symbol equations.
Comparing Anaerobic & Aerobic Respiration
The processes of aerobic and anaerobic respiration can be compared with regard to the need for oxygen, the products and the relative amounts of ATP produced/energy transferred
Aerobic | Anaerobic | |
|---|---|---|
Oxygen used | Yes | No |
Glucose breakdown | Complete | Incomplete |
Products | Carbon dioxide and water | In animal cells: lactic acid In yeast and plant cells: carbon dioxide and ethanol |
Relative amount of ATP produced/energy released per glucose molecule | A lot | A little |
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