Nephron Structure (Edexcel IGCSE Biology): Revision Note

Exam code: 4BI1

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Lucy Kirkham

Updated on

Nephrons

  • The kidney can be divided into three main regions: the cortex, the medulla and the renal pelvis

  • Nephrons are the functional units of the kidney. Each kidney has around one million nephrons

  • The nephron is responsible for filtering the blood and forming urine

  • Some parts of the nephron are located in the cortex, and some parts are located in the medulla: 

    • The Bowman’s capsule, glomerulus, PCT, and DCT are found in the cortex, which is the outermost layer of the kidney

    • The loop of Henle and collecting duct are found mainly in the medulla, the inner region of the kidney

  • The renal pelvis is a funnel-shaped cavity that collects urine from the collecting ducts and passes it into the ureter

The structure of a nephron

  • The main parts of a nephron are:

    • Bowman's capsule, which surround the glomerulus

    • Proximal convoluted tubule (PCT)

    • Loop of Henle

    • Distal convoluted tubule (DCT)

    • Collecting duct

Diagram of human kidneys showing position in the body and labelled kidney structure, including cortex, medulla, adrenal gland, renal vessels and ureter.
Structure of a nephron
Nephron structure

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Lucy Kirkham

Reviewer: Lucy Kirkham

Expertise: Content Creator

Lucy has been a passionate Maths teacher for over 12 years, teaching maths across the UK and abroad helping to engage, interest and develop confidence in the subject at all levels.Working as a Head of Department and then Director of Maths, Lucy has advised schools and academy trusts in both Scotland and the East Midlands, where her role was to support and coach teachers to improve Maths teaching for all.