Biological Molecules (OCR A Level Biology): Exam Questions

Exam code: H420

3 hours43 questions

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1
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1 mark

Which of the following is not a property of water?

  • High specific heat capacity

  • Excellent solvent

  • Low latent heat of vaporisation

  • High surface tension

2
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Which of the following best describes the bonding between amino acids in the tertiary structure of a protein?

  • Hydrogen and ionic bonds, disulfide bridges and hydrophobic interactions.

  • Glycosidic, peptide and hydrogen bonds.

  • Ionic and glycosidic bonds, and disulfide bridges.

  • Peptide and glycosidic bonds, hydrophobic interactions and disulfide bridges.

3
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Which of the following is an example of a fibrous protein?

  • Elastin

  • Haemoglobin

  • Enzymes

  • Insulin

4
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Carbohydrates, such as starch, are made from monosaccharides joined together. Which of the following types of bond joins monosaccharides together?

  • Peptide

  • Ester

  • Glycosidic

  • Phosphodiester

5
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Which biological molecule is tested for using the emulsion biochemical test?

  • Lipid

  • Protein

  • Reducing sugars

  • Starch

1
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Which of the following reactions, A to D, describes the conversion of a polymer to a monomer?

q10-paper-2-nov-2020-ocr-a-level-biology
    2
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    Collagen is found in tendons. Tendons attach muscles to bones. Which of the following lists of properties, A to D, makes collagen suitable for this role?

    • strong, inflexible, insoluble

    • strong, flexible, soluble

    • strong, inflexible, soluble

    • strong, flexible, insoluble

    3
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    The following are a series of organic molecules and the chemical processes that occur to convert them into different molecules.

    Which of the rows, A to D, is correct?

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      The following table describes the approximate percentage mass of different chemical elements in organic polymers. 

       

      Polymer

      N (%)

      C (%)

      O (%)

      H (%)

      P (%)

      A

      nucleic acid

      20.0

      30.0

      20.0

      10.0

      20.0

      B

      carbohydrate

      0.0

      33.3

      33.3

      33.3

      0.0

      C

      protein

      30.0

      10.0

      10.0

      0.0

      50.0

      D

      lipid

      0.0

      50.0

      49.0

      1.0

      0.0

      Which of the rows, A to D, is correct?

        5
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        Which of the following processes involves the formation of ester bonds?

        1   synthesis of polynucleotides 2   synthesis of triglycerides 3   synthesis of polypeptides

        • 1, 2 and 3

        • Only 1 and 2

        • Only 2 and 3

        • Only 1

        6
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        Which of the following could not be an amino acid?

        q5-paper-2-june-2018-ocr-a-level-biology
          7
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          Lipids are a diverse group of chemicals that are neither polar nor charged and hence are insoluble in water. The ___(1)___ nature of the heads of phospholipids allows them to form membranes. ___(2)___ also contain fatty acids and form part of the membrane. Lipids can be used for energy storage in the form of ___(3)___. Some hormones are also lipids and they are similar in structure to ___(4)___.

          Which row shows the correct sequence of missing words?

           

          1

          2

          3

          4

          A

          hydrophilic

          glycolipids

          triglycerides

          cholesterol molecules

          B

          hydrophilic

          triglycerides

          cholesterol molecules

          glycolipids

          C

          hydrophobic

          cholesterol molecules

          triglycerides

          bile

          D

          hydrophilic

          cholesterol molecules

          triglycerides

          glycolipids

            8
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            Which of the statements, A to D, correctly describes the process of adhesion?

            • attraction of water molecules to the impermeable walls of xylem tissue

            • attraction of water molecules to other water molecules in the xylem tissue

            • active transport of water molecules into phloem tissue

            • attraction of water molecules to other water molecules in the phloem tissue

            9
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            Which of the statements, A to D, about amylopectin is correct?

            • it contains 1-4 and 1-6 glycosidic bonds between α-glucose monomers

            • it is an unbranched chain of α-glucose monomers

            • it contains α 1-4 and β 1-6 glycosidic bonds

            • it is made up of β-glucose monomers and is uncoiled

            10
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            An unknown solution of a single sugar was tested. The results were recorded in Table 9.1.

            Colours observed after testing

            Benedict’s test for reducing sugars

            Benedict’s test for non-reducing sugars

            blue

            brick red

            Table 9.1

            Identify the unknown sugar.

            • fructose

            • lactose

            • sucrose

            • glucose

            11
            1 mark

            The diagram shows the structures of two molecules.

            q1-hard-2-2

            Which of the following statements correctly identifies a difference between molecule 1 and molecule 2?

            • Molecule 1 contains a glycerol backbone, whereas molecule 2 does not.

            • Molecule 1 contains a phosphate group, a nitrogen-containing group and two fatty acid chains, whereas molecule 2 contains three fatty acid chains but no phosphate group or nitrogen-containing group.

            • Molecule 1 contains only saturated fatty acid chains, whereas molecule 2 contains an unsaturated fatty acid chain.

            • Molecule 1 is hydrophilic, whereas molecule 2 has both hydrophilic and hydrophobic regions.

            12
            1 mark

            A student carried out biochemical tests on four unknown solutions (1–4). The results are shown in the table below.

            Solution

            Benedict's test

            Biuret test

            Iodine test

            Emulsion test

            1

            Brick-red precipitate

            Blue

            Blue-black

            Cloudy white

            2

            Blue

            Purple/lilac

            Brown

            Clear

            3

            Brick-red precipitate

            Purple/lilac

            Brown

            Clear

            4

            Blue

            Blue

            Blue-black

            Cloudy white

            Which option correctly identifies the components present in solution 3.

            • Reducing sugar, protein and starch only

            • Reducing sugar only

            • Reducing sugar and protein only

            • Protein and lipid only

            13
            1 mark

            A student carried out biochemical tests on four unknown solutions (1–4). The results are shown in the table below.

            Solution

            Benedict's test

            Biuret test

            Iodine test

            Emulsion test

            1

            Brick-red precipitate

            Blue

            Blue-black

            Cloudy white

            2

            Blue

            Purple/lilac

            Brown

            Clear

            3

            Brick-red precipitate

            Purple/lilac

            Brown

            Clear

            4

            Blue

            Blue

            Blue-black

            Cloudy white

            A student observes that solutions 1 and 4 both gave a blue-black colour with iodine and a cloudy white emulsion with ethanol.

            Which of the following correctly describes the structural features of the molecules responsible for these results in solutions 1 and 4?

            • The molecule responsible for the iodine result has a 1,4 and 1,6 glycosidic bonds forming a branched structure; the molecule responsible for the emulsion result is formed from one glycerol and three fatty acid molecules joined by ester bonds and is polar

            • The molecule responsible for the iodine result is a polysaccharide with a helical structure that traps iodine molecules; the molecule responsible for the emulsion result is a triglyceride formed by condensation reactions and is non-polar

            • The molecule responsible for the iodine result is a polysaccharide made of β-glucose monomers joined by 1,4 glycosidic bonds; the molecule responsible for the emulsion result is a triglyceride formed by hydrolysis reactions

            • The molecule responsible for the iodine result has a helical structure stabilised by hydrogen bonds between glucose monomers; the molecule responsible for the emulsion result is formed from glycerol and fatty acids joined by peptide bonds

            14
            1 mark

            Which row correctly identifies the molecules and one function of each?

            Four molecular structures: 1. Hexagonal C and H compound. 2. Monomer chain. 3. Phospholipid with carbon chains. 4. Amino acid with NH2 and COOH groups.

            Row

            Molecule 1

            Molecule 2

            Molecule 3

            Molecule 4

            A

            β-glucose; monomer of cellulose

            Cellulose; energy storage in plant cells

            Triglyceride; long term energy storage

            Amino acid; monomer of enzymes

            B

            α-glucose; monomer of starch

            Cellulose; structural support in plant cell walls

            Phospholipid; forms bilayer of cell membranes

            Nucleotide; monomer of nucleic acids

            C

            β-glucose; monomer of cellulose

            Glycogen; energy storage in animal cells

            Triglyceride; long term energy storage

            Nucleotide; monomer of nucleic acids

            D

            α-glucose; monomer of starch

            Cellulose; structural support in plant cell walls

            Phospholipid; forms bilayer of cell membranes

            Amino acid; monomer of enzymes

              1
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              Some of the properties of water make it a vital component of certain organelles such as the matrix in mitochondria. 

              Which of the following statements does not describe a useful property of water in the mitochondria?

              • Water is adhesive.

              • Water is a liquid.

              • Water is a substrate for reactions

              • Water is a polar solvent.

              2
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              Fibroin, the protein found in silk, mainly consists of amino acids in anti-parallel beta-sheets.

              Which of the following statements explains why haemoglobin has a more complex structure than fibroin?

              1

              Fibroin has a basic, repeating structure.

              2

              Interactions between R-groups when forming haemoglobin are within and between protein molecules.

              3

              The quaternary structure of haemoglobin is formed from folding of the secondary structure.

              4

              In fibroin, hydrogen bonds only form between the amino group and R group of the amino acids.

              • All 4 statements.

              • Statements 1, 2 and 3.

              • Statements 1, 2 and 4

              • Statements 1 and 2 only.

              3
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              Chitin is a structural polysaccharide that is found in the cell walls of fungi. The chemical structure of chitin is shown below, it shares some similarities with the structure of cellulose.

              ocr-a-2-2h-mcq-chitin-structure

              Which of the following statements accurately compares the structures of cellulose and chitin?

              • Chitin contains α-glycosidic bonds, cellulose contains β-glycosidic bonds.

              • Chitin contains nitrogen, cellulose does not.

              • Chitin contains 1-4 glycosidic bonds, cellulose contains 1-6 glycosidic bonds.

              • Chitin does not have branching, cellulose has branching.

              4
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              A patient is experiencing the following symptoms:

              • Muscle cramps

              • Seizures

              • Headaches

              • Increased urine production.

              Which of the following ions is likely to be deficient in this patient?

              • Na+

              • HCO3-

              • NH4+

              • H+

              5
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              Sickle cell anaemia is a genetic disease affecting red blood cells which is caused by base substitution in the haemoglobin protein which results in a polar amino acid being replaced with a non-polar amino acid in the globin subunits.

              The diagram below shows the difference between a normal red blood cell and a sickle cell.

              ocr-a-2-2h-mcq-q5-red-blood-cell-diagram

              Which of the following statements correctly explain the impact of the amino acid substitution?

              • The haemoglobin becomes less soluble.

              • The haemoglobin subunits lose their prosthetic groups.

              • The disulfide bonds holding the subunits together break.

              • The haemoglobin becomes less compact.