Chemicals & Life (Cambridge (CIE) IGCSE Combined Science: Biology): Revision Note

Exam code: 0653

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Jenna Quinn

Updated on

Chemical elements

  • Most of the molecules in living organisms fall into three categories: carbohydrates, proteins and lipids

  • These all contain carbon and so are described as organic molecules

Chemical elements table

Molecule

Chemical elements

Carbohydrate

  • Carbon (C)

  • Oxygen (O)

  • Hydrogen (H)

Protein

All contain:

  • Carbon (C)

  • Oxygen (O)

  • Hydrogen (H)

  • Nitrogen (N)

Some contain small amounts of other elements, for example:

  • Sulfur (S)

  • Selenium (Se)

Lipid

  • Carbon (C)

  • Oxygen (O)

  • Hydrogen (H)

Large molecules are made from smaller molecules

Carbohydrates

  • Long chains of simple sugars (monosaccharides)

  • Glucose is a simple sugar

  • When two glucose molecules join together maltose is formed (a disaccharide)

  • When lots of glucose molecules join together starch, glycogen or cellulose can form (a polysaccharide)

 

Diagram showing three carbohydrates (all long chains of glucose molecules joined together) in cells: animal cells (exemplified by a liver cell) storing glycogen in glycogen granules and plant cells (exemplified by a palisade mesophyll cell) storing starch in starch grains in the chloroplasts and cellulose used in the cell wall .
Glycogen, cellulose and starch are all made from glucose molecules

Fats

  • Most fats (lipids) in the body are made up of triglycerides

  • Their basic unit is one glycerol molecule chemically bonded to three fatty acid chains

  • The fatty acids vary in size and structure

  • Lipids are divided into fats (solids at room temperature) and oils (liquids at room temperature)

Diagram of a triglyceride showing a vertical glycerol backbone joined to three long hydrocarbon fatty acid tails.
Structure of a triglyceride

Proteins

  • Long chains of amino acids

  • There are about 20 different amino acids

  • They all contain the same basic structure but the ‘R’ group is different for each one

  • When amino acids are joined together a protein is formed

  • The amino acids can be arranged in any order, resulting in hundreds of thousands of different proteins

  • Even a small difference in the order of the amino acids results in a different protein being formed

Diagram of the general amino acid structure showing a central carbon with four chemical bonds, one with an NH₂ amino group to the left,  H above, a COOH carboxyl group to the right and R group to the bottom.
General amino acid structure
Diagram showing separate coloured circles representing individual amino acids, coloured circles attached to each other representing amino acids joined together to form a peptide chain, and finally a long peptide chain folded into a complex protein, titled “How your body uses amino acids”.
Amino acids join together to form proteins

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Jenna Quinn

Reviewer: Jenna Quinn

Expertise: Content Creator

Jenna studied at Cardiff University before training to become a science teacher at the University of Bath specialising in Biology (although she loves teaching all three sciences at GCSE level!). Teaching is her passion, and with 10 years experience teaching across a wide range of specifications – from GCSE and A Level Biology in the UK to IGCSE and IB Biology internationally – she knows what is required to pass those Biology exams.