Exam code: 4SD0
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Define stimulus.
A change in the environment that can be detected by an organism — for example light, temperature, sound, chemicals or touch.

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Define receptor.
A structure that detects a stimulus.
In humans, receptors are found in the sense organs.
Why must organisms respond to changes in their environment?
In order to survive — for example escaping predators, finding food, or maintaining internal conditions.
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Define stimulus.
A change in the environment that can be detected by an organism — for example light, temperature, sound, chemicals or touch.
Define receptor.
A structure that detects a stimulus.
In humans, receptors are found in the sense organs.
Why must organisms respond to changes in their environment?
In order to survive — for example escaping predators, finding food, or maintaining internal conditions.
How do plants detect stimuli?
Using specialised cells that detect stimuli such as light, gravity or water.
Give three examples of a response to a stimulus.
Moving towards or away from something
Secreting chemicals
Adjusting body processes
Name five stimuli an organism might detect.
Light
Temperature
Sound
Chemicals
Touch
Where are receptors found in humans?
In the sense organs.
A change in the environment that an organism can detect is called a ________.
A change in the environment that an organism can detect is called a stimulus.
Stimuli are detected by ________, which in humans are found in the sense organs.
Stimuli are detected by receptors, which in humans are found in the sense organs.
True or False?
Only animals can detect and respond to stimuli.
False.
Plants also detect stimuli, using specialised cells sensitive to light, gravity and water.
True or False?
Responding to stimuli improves an organism's chance of survival.
True.
It lets the organism escape predators, find food and keep its internal conditions within safe limits.
Put stimulus, receptor and response in the correct order.
Stimulus ➔ receptor ➔ response
Define homeostasis.
The maintenance of a constant internal environment.
Why is homeostasis essential?
It keeps optimal conditions for enzyme activity and cell function, letting the organism survive and respond to change.
If conditions go beyond set limits, the organism may die.
Give two examples of homeostasis in humans.
Control of body temperature
Control of body water content
What is the human core body temperature?
Close to 37 °C.
Why must body temperature be kept close to 37 °C?
Because the body's enzymes work best at this temperature — much above it they denature, and much below it reactions become too slow.
How does the skin help to cool the body when it is too hot?
Sweat is released and evaporates, taking heat energy away from the body
Vasodilation — blood vessels near the skin surface widen, so more heat is lost
By which three routes does the body lose water?
The lungs, in breathed-out air
The skin, in sweat
The kidneys, in urine
Define internal environment.
The conditions inside the body that surround the cells, such as temperature and water content.
What three things are needed for a co-ordinated response?
A stimulus
A receptor
An effector
What is the job of an effector?
It carries out the response — for example a muscle contracting or a gland releasing a hormone.
Give one example of an organism responding to a change in its environment.
A plant shoot growing towards light, or a person shivering when the air turns cold.
A ________ is a change in the environment that a receptor detects.
A stimulus is a change in the environment that a receptor detects.
When the body is too cold, blood vessels near the skin surface narrow — this is called ________.
When the body is too cold, blood vessels near the skin surface narrow — this is called vasoconstriction.
True or False?
Homeostasis is under conscious control.
False.
Homeostasis is involuntary — you do not consciously maintain your body temperature or water content.
True or False?
Homeostasis means the internal environment never changes at all.
False.
Conditions fluctuate slightly around a set level — homeostasis keeps them within narrow limits, not perfectly fixed.
What three things does a co-ordinated response require?
A stimulus — a change in the environment
A receptor — which detects the stimulus
An effector — a muscle or gland that brings about the response
What is an effector?
A muscle or gland that brings about a response to restore optimum levels.
Which part of the body processes information from receptors?
The central nervous system — the brain and the spinal cord.
Why is homeostasis described as involuntary control?
Because it is automatic — the brain and spinal cord maintain it without any conscious thought.
Which two types of response can automatic control systems use?
Nervous responses
Chemical responses, for example via hormones
Give two examples of a stimulus in a homeostatic response.
A change in glucose levels in the blood
A change in body temperature
What does the central nervous system do in a response?
It receives and processes information from the receptors, then sends impulses out to the effectors.
An ________ is a muscle or gland that brings about a response.
An effector is a muscle or gland that brings about a response.
Impulses from receptors travel into the central nervous ________, made up of the brain and spinal cord.
Impulses from receptors travel into the central nervous system, made up of the brain and spinal cord.
True or False?
All co-ordinated responses use the nervous system.
False.
Some are nervous responses, but others are chemical responses carried by hormones.
True or False?
A receptor and an effector do the same job.
False.
A receptor detects the stimulus; an effector — a muscle or gland — carries out the response.
Put the parts of a co-ordinated response in order.
Stimulus ➔ receptor ➔ effector ➔ response
Define tropism.
A directional growth response made by a plant to a stimulus such as light or gravity.
What makes a tropism positive or negative?
Positive — growth towards the stimulus
Negative — growth away from the stimulus
Why do plants need to respond to light and gravity?
To ensure their leaves absorb light for photosynthesis, and that shoots grow upwards while roots grow downwards.
Define phototropism.
Growth towards or away from the direction of a light source.
Define geotropism.
Growth towards or away from the source of gravity. Also called gravitropism.
Which tropisms do shoots show, and why?
Positive phototropic and negative geotropic — they grow upwards, towards light, so the leaves can absorb sunlight.
Which tropisms do roots show, and why?
Negative phototropic and positive geotropic — they grow downwards into the soil, to anchor the plant and absorb water and minerals.
Define auxin.
A plant growth regulator, similar to an animal hormone, that co-ordinates and controls directional growth responses such as phototropism.
Where is auxin made, and where does it act?
It is mostly made in the tips of growing shoots, then diffuses down to the region just below the tip where cell division occurs.
What effect does auxin have on cells?
It stimulates them to elongate — get longer. The more auxin present, the faster they elongate and grow.
Explain how a shoot bends towards a light source.
When light shines predominantly from one side, auxin made in the tip concentrates on the shaded side.
Cells on the shaded side elongate faster than those on the sunny side.
This unequal growth makes the shoot bend towards the light.
What happens if light shines evenly all around a shoot tip?
Auxin is distributed evenly, so the cells grow at the same rate and the shoot grows straight up.
In a shoot lit from one side, auxin concentrates on the ________ side.
In a shoot lit from one side, auxin concentrates on the shaded side.
Roots show a positive ________ response, growing downwards towards gravity.
Roots show a positive geotropic response, growing downwards towards gravity.
True or False?
Auxin makes a shoot bend by increasing the number of cells.
False.
Auxin causes the cells that already exist to elongate. It does not increase the overall number of cells.
True or False?
Only the region behind the tip of a shoot contributes to growth.
True.
Cell division and cell elongation happen just below the tip, which is where auxin diffuses to.
Name the two control systems that respond to stimuli in humans.
The nervous system
The hormonal system, also called the endocrine system
How is information sent through the nervous system?
As electrical impulses, which pass very quickly along nerve cells called neurones.
How is information sent through the endocrine system?
As chemical substances called hormones, carried in the blood so they circulate round the whole body.
Define gland.
A group of cells that produces and releases one or more substances — a process known as secretion.
Which system controls functions needing an instant response?
The nervous system — for example the withdrawal reflex when a hand touches a flame.
What do hormones act on?
One or more specific target organs, whose activity they alter.
Compare what the nervous and endocrine systems are made of.
Nervous system — nerves (bundles of neurones), the brain and the spinal cord
Endocrine system — glands
Compare the speed of the nervous and endocrine systems.
Nervous — very fast
Endocrine — slower
Compare the type of effect each system has.
Nervous — specific and localised, acting on particular cells
Endocrine — widespread, affecting many cells or organs
Compare how long the effects of each system last.
Nervous — short, stopping quickly
Endocrine — long, lasting until the hormone is broken down
Hormones are transported around the body in the ________.
Hormones are transported around the body in the blood.
Electrical impulses pass along nerve cells called ________.
Electrical impulses pass along nerve cells called neurones.
True or False?
Hormonal responses are faster than nervous responses.
False.
Nervous responses are very fast; hormonal responses are slower but last longer.
True or False?
A hormone can affect many organs at once.
True.
Because hormones travel in the blood to the whole body, their effects are widespread.
What two structures make up the central nervous system?
The brain
The spinal cord
What is the peripheral nervous system?
All of the nerves that branch out from the CNS to the rest of the body.
Define nerve.
A bundle of neurones.
How is information transmitted through the nervous system?
As electrical impulses — fast-moving electrical signals that pass along cells called neurones.
What is the role of the CNS?
It acts as the central co-ordinating centre, processing incoming information from the sense organs and co-ordinating the body's response.
What happens when a receptor is stimulated?
It produces electrical impulses, which travel along sensory neurones to the CNS.
Which neurones carry impulses away from the CNS?
Motor neurones, which carry impulses to the effectors — muscles or glands.
Give the full pathway of a nervous response.
Stimulus ➔ receptor ➔ sensory neurone ➔ CNS ➔ motor neurone ➔ effector ➔ response
What does an effector do?
It carries out the response — for example a muscle contracts or a gland secretes.
Name five stimuli that receptors in sense organs detect.
Light
Sound
Touch
Temperature
Chemicals
The central nervous system consists of the brain and the ________.
The central nervous system consists of the brain and the spinal cord.
Impulses travel to the CNS along ________ neurones.
Impulses travel to the CNS along sensory neurones.
True or False?
A nerve and a neurone are the same thing.
False.
A neurone is a single nerve cell. A nerve is a bundle of neurones.
True or False?
Nerves link the CNS to the sense organs.
True.
Nerves extend from the CNS to all areas of the body, including the sense organs, allowing communication between the brain and the rest of the body.
Define synapse.
The tiny gap between two neurones.
Define neurotransmitter.
A chemical messenger released at a synapse that carries the signal from one neurone to the next.
Describe how an impulse crosses a synapse.
The electrical impulse reaches the end of one neurone and triggers the release of neurotransmitters.
These diffuse across the synapse and bind to the next neurone.
This causes a new electrical impulse to be generated.
Why are neurotransmitters needed at all?
Because neurones are not directly connected to each other — there is a gap, so the signal cannot pass electrically.
By which process do neurotransmitters cross the synapse?
Diffusion.
What triggers the release of neurotransmitters?
An electrical impulse arriving at the end of a neurone.
What happens after a neurotransmitter binds to the next neurone?
A new electrical impulse is generated, so the signal continues along the pathway.
The tiny gap between two neurones is called a ________.
The tiny gap between two neurones is called a synapse.
Neurotransmitters cross the synapse by ________ and bind to the next neurone.
Neurotransmitters cross the synapse by diffusion and bind to the next neurone.
True or False?
An electrical impulse jumps directly across a synapse.
False.
The signal crosses chemically, carried by neurotransmitters that diffuse across the gap, before a new impulse is generated.
True or False?
Neurotransmitters are chemical messengers.
True.
They are released at the end of one neurone and bind to the next, passing the signal on.
Are neurones directly connected to one another?
No. They are separated by a synapse, a tiny gap.
Define reflex response.
An involuntary response that does not involve the conscious part of the brain as the co-ordinator.
Awareness of it comes after the response has happened.
Define reflex arc.
The pathway taken by electrical impulses during a reflex action.
Why are reflex responses useful?
They are automatic and rapid, which helps minimise damage to the body and aids survival.
Give three examples of reflex responses.
Pain withdrawal
Blinking
Coughing
Describe the reflex arc for withdrawing a finger from a hot object.
A receptor in the skin detects the stimulus.
A sensory neurone sends impulses to the spinal cord, which acts as the co-ordinator.
The impulse passes to a relay neurone in the spinal cord.
The relay neurone synapses with a motor neurone.
The motor neurone carries the impulse to a muscle (the effector), which contracts and pulls the finger away.
Which structure acts as the co-ordinator in a reflex arc?
The spinal cord, part of the CNS — not the conscious part of the brain.
Which neurone sits between the sensory and motor neurones?
The relay neurone, in the spinal cord.
What is the effector in a withdrawal reflex?
A muscle, which contracts to pull the body part away from the harmful stimulus.
Give the order of structures in a reflex arc.
Stimulus ➔ receptor ➔ sensory neurone ➔ relay neurone ➔ motor neurone ➔ effector ➔ response
In a reflex arc, the impulse passes to a ________ neurone in the spinal cord.
In a reflex arc, the impulse passes to a relay neurone in the spinal cord.
A reflex response is also known as an ________ response.
A reflex response is also known as an involuntary response.
True or False?
You are aware of a reflex before it happens.
False.
Awareness of a reflex comes after the response has already been carried out — which is what makes it so fast.
True or False?
Blinking is a reflex response.
True.
Like coughing and pain withdrawal, it is automatic and helps avoid serious injury — in this case damage to the eye.
Why is the eye described as a sense organ?
It is a highly specialised organ containing receptor cells that allow us to detect the stimulus of light.
What is the function of the conjunctiva?
A clear membrane covering the white of the eye and the inside of the eyelids.
It lubricates the eye and protects it from external irritants.
What is the function of the cornea?
A transparent, curved layer at the front of the eye that refracts light as it enters.
What is the function of the sclera?
The strong outer wall of the eyeball. It keeps the eye in shape and provides attachment for the muscles that move the eye.
What is the function of the pupil?
A circular opening in the centre of the iris that allows light to enter the eye.
What is the function of the iris?
It controls how much light enters the pupil.
What is the function of the lens?
A transparent disc that can change shape to focus light onto the retina.
What is the function of the ciliary muscle?
A ring of muscle that contracts and relaxes to change the shape of the lens.
What is the function of the suspensory ligaments?
They connect the ciliary muscle to the lens.
What is the function of the retina?
It contains the receptor cells sensitive to light.
In which order does light pass through the eye?
Cornea ➔ pupil ➔ lens ➔ retina
Impulses then leave the eye along the optic nerve.
What is the function of the optic nerve?
It carries impulses between the eye and the brain.
What is the blind spot?
The point where the optic nerve leaves the eye, at which there are no light receptor cells.
Light-sensitive receptor cells are found in the ________ of the eye.
Light-sensitive receptor cells are found in the retina of the eye.
Light is refracted as it enters the eye by the transparent, curved ________.
Light is refracted as it enters the eye by the transparent, curved cornea.
True or False?
The suspensory ligaments are muscles.
False.
They are ligaments connecting the ciliary muscle to the lens — they tighten or loosen, they do not contract.
True or False?
There are no light receptor cells at the blind spot.
True.
It is the point where the optic nerve leaves the eye.
Define accommodation.
The way the lens brings about the fine focusing of light onto the retina.
How is the shape of the lens changed?
The lens is elastic. The ciliary muscles contract or relax, which makes the suspensory ligaments tighten or loosen and so changes the lens shape.
Describe how the eye focuses on a close-up object.
The ciliary muscles contract, so the ring of muscle decreases in diameter.
The suspensory ligaments loosen, so they stop pulling on the lens.
The lens becomes thicker, and light is refracted more.
Describe how the eye focuses on a distant object.
The ciliary muscles relax, so the ring of muscle increases in diameter.
The suspensory ligaments tighten and pull on the lens.
The lens becomes thinner, and light is refracted less.
What is the purpose of the pupil reflex?
To protect the retina from damage by controlling how much light enters the eye.
What happens to the pupil in dim light, and why?
It dilates (widens), to let as much light as possible into the eye and improve vision.
What happens to the pupil in bright light, and why?
It constricts (narrows), to stop too much light entering and damaging the retina.
Why can you not see clearly for a moment in bright sunlight?
The pupil takes a moment to constrict.
Until it does, too much light reaches the retina.
Which part of the eye changes the size of the pupil?
The iris, a ring of muscle surrounding the pupil.
To focus on a near object the ciliary muscles contract and the lens becomes ________.
To focus on a near object the ciliary muscles contract and the lens becomes thicker.
In bright light the pupil ________ to protect the retina from damage.
In bright light the pupil constricts to protect the retina from damage.
True or False?
The suspensory ligaments contract to change the lens shape.
False.
Suspensory ligaments are not muscles — they tighten or loosen. It is the ciliary muscles that contract and relax.
True or False?
The pupil reflex is an example of a reflex action.
True.
It happens automatically, without conscious thought, to protect the retina.
Which lens shape refracts light more, and when is it used?
A thicker (fatter) lens refracts light more, and is used when focusing on near objects.
Why is the skin described as our largest sense organ?
It contains many receptors that detect external stimuli, including touch, pressure, pain, heat and cold.
Define vasodilation.
When the muscles in the walls of the arterioles near the skin relax, so the arterioles widen and more blood flows through the skin capillaries.
Define vasoconstriction.
When the muscles in the walls of the arterioles near the skin contract, so the arterioles narrow and less blood flows through the skin capillaries.
How does vasodilation cool the body?
A greater volume of blood flows through the capillaries near the skin surface, so more heat is lost to the environment by radiation.
How does vasoconstriction reduce heat loss?
A smaller volume of blood reaches the skin capillaries, so less heat is lost by radiation.
How does sweating cool the body?
Sweat is secreted by the sweat glands and evaporates, using heat energy from the body to convert liquid water into water vapour.
Describe how the skin responds when a person enters a hot room.
Vasodilation — arterioles supplying the skin capillaries widen, so more blood flows near the surface and heat is lost by radiation.
Sweating — sweat evaporates from the skin surface, cooling the body.
Describe how the skin responds in a cold environment.
Vasoconstriction — arterioles supplying the skin capillaries narrow, reducing blood flow to the skin and so reducing heat loss.
Sweating decreases — less sweat is produced, so less heat is lost by evaporation.
Why is vasoconstriction not strictly a warming mechanism?
It does not raise the temperature of the blood — it only reduces heat loss from blood flowing through the skin.
Why does sweating stop cooling you on a very humid day?
Sweat only cools the body when it evaporates.
In humid air the water vapour cannot escape easily, so evaporation slows and less heat is removed.
Where are the receptors that detect a change in temperature?
In the skin, which contains both heat receptors and cold receptors.
Why must core body temperature be tightly controlled?
Because the body's enzymes work best close to 37 °C — far above it they denature, and far below it reactions become too slow.
During ________ the arterioles near the skin widen so more heat is lost by radiation.
During vasodilation the arterioles near the skin widen so more heat is lost by radiation.
Sweat cools the skin as it ________, using heat energy from the body.
Sweat cools the skin as it evaporates, using heat energy from the body.
True or False?
Vasodilation means the capillaries in the skin get wider.
False.
It is the arterioles that widen. That lets more blood flow through the skin capillaries.
True or False?
Heat exchange happens at the body's surface.
True.
The surface is where the blood comes into closest proximity to the environment, so it is where heat is both lost and gained.
Define hormone.
A chemical substance produced by a gland and carried by the blood, which alters the activity of one or more specific target organs.
Where is adrenaline produced, and what is its role?
In the adrenal gland.
It readies the body for a 'fight or flight' response, in situations where the body may be in danger.
Give four effects of adrenaline.
Increased heart and breathing rate, delivering glucose and oxygen faster
Blood flow redirected to the muscles, away from non-essential organs
Dilation of blood vessels in the muscles
Breakdown of stored glycogen to glucose in the liver and muscle cells
Where is insulin produced, and what is its role?
In the pancreas, which acts as an endocrine gland.
Its role is to lower blood glucose levels.
Describe what happens when blood glucose gets too high.
Cells in the pancreas detect the rise and secrete insulin into the blood.
Insulin stimulates the muscles and liver to take up glucose and store it as glycogen.
Blood glucose falls back to normal, and the pancreas stops secreting insulin.
Why is a blood glucose level that is too high dangerous?
Cells of the body can lose water by osmosis.
Why is a blood glucose level that is too low dangerous?
The brain receives insufficient glucose for respiration, which can lead to a coma or even death.
Where is testosterone produced, and what is its role?
In the male testes.
It stimulates the development of the male reproductive organs and the secondary sexual characteristics in males — facial, pubic and underarm hair, deepening of the voice, and increased muscle mass.
Where is progesterone produced, and what is its role?
In the female ovaries.
It maintains the uterine lining during pregnancy and prevents further ovulation.
Where is oestrogen produced, and what is its role?
In the female ovaries.
It causes the secondary sexual characteristics in females — breast development, wider hips, pubic and underarm hair — and helps regulate the menstrual cycle.
How does oestrogen help regulate the menstrual cycle?
It stimulates the repair and thickening of the uterus lining after menstruation, preparing it to receive a fertilised egg.
Which two organs work together to control blood glucose levels?
The pancreas
The liver
Insulin causes excess blood glucose to be stored in the liver and muscles as ________.
Insulin causes excess blood glucose to be stored in the liver and muscles as glycogen.
Adrenaline is produced by the ________ gland.
Adrenaline is produced by the adrenal gland.
True or False?
The pancreas only produces hormones.
False.
It acts as an endocrine gland, secreting insulin into the blood, but it also has a separate digestive role, secreting enzymes into the digestive system.
True or False?
Control of blood glucose is an example of homeostasis.
True.
Blood glucose concentration must be kept within a narrow range, just like core body temperature.
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