Circulatory Systems, Heart & Blood Vessels (Cambridge (CIE) IGCSE Biology): Exam Questions

Exam code: 0610 & 0970

4 hours54 questions

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1a
1 mark

Fig. 1 shows a section through a blood vessel.

BDZJNnEY_image

Fig. 1

Identify the type of blood vessel shown in Fig. 1.

1b
3 marks

Red blood cells are different to white blood cells.

State three ways in which a red blood cell is different to a white blood cell.

1c
4 marks

Blood has many components.

(i)

State the name of the liquid component of blood.

[1]

(ii)

State three substances that are transported in the liquid component of blood.

[3]

2a
3 marks

Blood circulates around the body in arteries, veins and capillaries.

Place ticks (✓) in the correct boxes in Table 1 to show the features of arteries.

Table 1

structure and function

arteries

carries blood at high pressure

 

carries blood towards the heart

 

has a thick wall

 

has a narrow lumen

 

has valves present throughout the vessel

 

2b
3 marks

Fig. 1 shows a photomicrograph of a capillary with red blood cells passing through it.

097031-may-2019-paper-3-q7b-capillary---sq

Fig. 1

(i)

State the function of the red blood cells shown in Fig. 1.

[1]

(ii)

Red blood cells are one component of blood.

State the names of two other components of blood.

[2]

3a
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4 marks

A student completed different types of activity.

She measured her pulse rate during each type of activity in beats per minute (bpm).

The results are shown in Fig. 1.

2018-nov-s1-061031-q3a

Fig. 1

Use Fig. 1 to answer these questions.

(i)

State the type of activity that results in the highest pulse rate.

[1]

(ii)

State the pulse rate of the student when she was cycling. Give your answer in bpm.

[1]

(iii)

Calculate the percentage increase in her pulse rate between resting and walking.

Show your working and give your answer to the nearest whole number.

[2]

3b
1 mark

Measuring the pulse is one way of monitoring the activity of the heart.

State one other way of monitoring the activity of the heart.

3c
2 marks

Describe the changes to a person’s breathing during exercise.

4a
4 marks

The heart is part of the circulation system.

Fig. 1 shows a mammalian heart. 

4a-heart

Fig. 1

Identify structures labelled A to D on Fig. 1.

4b
1 mark

Identify the septum on Fig. 1 from part (a).

4c
1 mark

Extended only

Explain why the human circulation system is described as a double circulation system.

4d
2 marks

Extended only

Describe the function of the right side of the heart.

5a
2 marks

Describe how coronary heart disease affects the heart.

5b
3 marks

State three risk factors associated with coronary heart disease.

5c
2 marks

Identify two lifestyle changes that can reduce the risk of coronary heart disease.

5d
1 mark

Outline how an ECG can help detect signs of coronary heart disease.

6
1 mark

Measuring the pulse rate is one way of monitoring the activity of the heart.

State one other way of monitoring the activity of the heart.

7a
6 marks

Fig. 5.1 is a diagram of a human heart. 

Diagram of a heart showing four labelled blood vessels: A from the body, B to the lungs, C to the body, D from the lungs, with directional arrows.

Fig 5.1

(i) Use label lines and labels to identify these structures on Fig. 5.1: 

  • atrium 

  • septum 

  • ventricle

  • valve

 [4]

(ii) Identify the letter or letters of all the blood vessels from Fig. 5.1, that: 

are arteries ....................... 

is the pulmonary vein ....................... .

[2]

7b
4 marks

Coronary heart disease (CHD) is caused by a blockage of blood vessels in the heart.

(i) State the name of the blood vessels that become blocked. 

[1]

(ii) State three risk factors for developing CHD. 

[3]

1a
5 marks

A scientist investigated the effect of different types of activity on heart rate of participants aged 21 after they had completed the activity for 10 minutes. 

The results are shown in Fig. 1.

cie-igcse-2023-specimen-q2a

Fig. 1

(i) State two control variables the scientist should have ensured throughout the investigation. 

[2]

(ii) Describe the results of the investigation.

[3]

1b
3 marks

Describe how the scientist could have measured and recorded heart rate. 

1c
3 marks

Extended

Explain the effect swimming has on heart rate.

2a
6 marks

Extended Only

Fig. 1 shows a photomicrograph of human blood.

screenshot-2022-10-03-13-08-51

Fig. 1

Describe the differences in appearance and the functions of the three cells labelled in Fig. 1.

2b
3 marks

Extended Only

Fig. 2 shows some of the stages of blood clotting.

screenshot-2022-10-03-13-12-56

Fig. 2

(i) Complete Fig. 2 by filling in the two empty boxes.

[1]

(ii) State two roles of blood clotting.

[2]

3a
3 marks

Fig. 1 shows a photomicrograph of some red blood cells.

061032-oct-2018-paper-3-q8a-rbcs---sq

Fig. 1

(i) State the function of a red blood cell.

[1]

(ii) State two ways in which a red blood cell is adapted to its function.

[2]

3b
1 mark

State the name of a component of blood that is responsible for clotting.

3c
4 marks

(i) State the name of the disease caused by a blockage in the arteries supplying the heart muscle.

[1]

(ii) List three risk factors that increase the risk of a blockage in the arteries supplying the heart muscle.

[3]

3d
4 marks

Fig. 2 is a diagram of the circulatory system. The blood vessels are labelled with letters. 

061032-oct-2018-paper-3-q8d-circulatory-system---sq

Fig. 2

Complete Table 1 by identifying the letter of the named blood vessel in Fig. 2.

Table 1

name of blood vessel

letter

aorta

 

pulmonary artery

 

renal vein

 

vena cava

 

3e
4 marks

Describe how the structures of the circulatory system maintain a one-way flow of blood.

4a
2 marks

Compare the structural features of arteries and veins.

4b
1 mark

Fig. 1 below shows a structure in the mammalian lungs. The feature labelled P is an alveolus.

Diagram of a plant root hair with layers of cells; labels P and Q indicate specific sections, featuring epidermal and cortical cells with dotted regions.
Fig. 1

Identify the structure labelled Q.

4c
1 mark

State the function of the structure labelled Q in Fig. 1.

4d
1 mark

Suggest how the structure of capillaries enables efficient exchange of substances.

5a
3 marks

Fig. 1 shows a diagram of the heart with letters to identify some of the structures.

Diagram of a human heart cross-section, labelled A to H, showing chambers, vessels, and walls in a simplified anatomical representation.
Fig. 1

Identify the letter(s) of the structure(s) that:

(i) contain deoxygenated blood.

[1]

(ii) receive blood from the lungs.

[1]

(iii) are veins.

[1]

5b
1 mark

Extended Only

State the name of the valve located between chambers F and H in Fig. 1.

5c
2 marks

Extended Only

(i) Describe the location of the septum in the mammalian heart.

[1]

(ii) Explain the importance of the septum.

[1]

5d
2 marks

Extended Only

Describe how the heart muscle and valves function to pump blood through the heart.

6
4 marks

A student performed different types of activity.

She measured her heart rate during each type of activity in beats per minute (bpm).

The results are shown in Fig. 2.1.

9-1-image-mq6

(i)

State the type of activity that results in the highest heart rate in Fig. 2.1

[1]

(ii)

State the heart rate of the student when she was cycling.

................................................... bpm [1]

(iii)

Calculate the percentage increase in her heart rate between resting and walking.

.............................................................% [2]

7a
6 marks

Fig. 3.1 shows a photomicrograph of human blood.

Microscopic image showing various blood cells, including a labelled phagocyte, lymphocyte, and red blood cell, against a light background.

Describe the differences in appearance and the functions of the three cells labelled in Fig. 3.1.

7b
3 marks

Fig. 3.2 shows some of the stages of blood clotting.

9-1-theory-p4-mq7b

(i)

Complete Fig. 3.2 by filling in the two empty boxes.

[1]

(ii)

State two roles of blood clotting.

[2]

8a
6 marks

Mammals have a double circulation.

Fig. 2.1 is a diagram of a section through the heart of a mammal. The arrows show the direction of blood flow through the heart and blood vessels.

Diagram of human heart anatomy with labelled parts including septum, featuring arrows indicating blood flow. Labels: A, B, C, D, and point X.

(i)

State the name of the chamber of the heart with the thickest wall.

[1]

(ii)

D is a vein. State the name of this vein and describe its structure.

name .................................................................................................

description of structure ..................................................

[3]

(iii)

Identify the structure labelled X in Fig. 2.1 and state its role in the heart.

[2]

8b
6 marks

Fig. 2.2 is a diagram that shows the double circulation of a mammal. The arrows indicate the movement of oxygen and carbon dioxide in and out of the blood.

Diagram of blood circulation showing pathways through heart, lungs, and tissues. Includes labelled capillaries in lungs and respiring tissues.

(i) Shade the blood vessel in Fig. 2.2 that transports blood with the highest oxygen concentration.

[1]

(ii) Describe the evidence shown in Fig. 2.2 that the mammal has a double circulatory system.

[2]

(iii) Explain the advantages of a double circulation.

[4]

9
2 marks

The activity of the heart can be monitored by measuring the pulse rate. 

State two other ways of monitoring the activity of the heart.

10
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2 marks

During exercise, the heart rate also increases.

(i) Identify the component in the blood that carries oxygen to the muscles.

[1]

(ii) Identify the gas that is released by cells as a waste product.

[1]

1a
2 marks

The blood has many components. 

Fig. 1 shows a micrograph of a blood smear. 

GQBE1eM1_blood-micrograph

Fig. 1

On the diagram, identify a red blood cell and a white blood cell. 

1b
4 marks

Extended Tier Only

Platelets are a component of blood that have an important role in blood clotting. 

Describe the process of blood clotting by platelets. Include an explanation of the role played by the clot in protecting the body.

1c
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3 marks

Blood clots can sometimes form in veins around the body. This is called a venous thromboembolism (VTE) and can be associated with postoperative complications following surgery.

graph

Calculate the percentage decrease in VTE death rates between 2001 and 2017.

1d
4 marks

Extended Tier Only

Veins are a type of blood vessel found in mammals. 

Compare the structure and function of veins with that of arteries.

2a
2 marks

The coronary arteries supply the heart muscle tissue with blood.

Fig. 1 shows a coronary artery with a blockage. 

Diagram of a coronary artery showing the direction of blood flow with a blockage labelled, narrowing the artery and obstructing flow.

Fig. 1

Explain the effect this blockage could have on heart muscle cells.

2b
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3 marks

A blocked coronary artery can lead to coronary heart disease. 

Table 1 shows information about blood flow through coronary arteries in two people.

Person X was diagnosed with coronary heart disease while person Y does not have coronary heart disease.

Table 1

person

blood flow through coronary arteries /

cm3 min -1

X 

167

Y 

295

(i) Explain the difference in blood flow through the coronary arteries for persons X and Y.

[1]

(ii) Calculate the volume of blood flowing through the coronary arteries of person X in 1 hour.

Give your answer in dm3.

[2]

2c
4 marks

A blockage of the coronary artery can be caused by fatty deposits called ‘plaques’. Drugs called statins can be taken to help prevent a blockage. 

Fig. 2 shows the effects of the treatment of one person with four different statins (ABC and D) over a period of 10 years. The arrows show when each new treatment was started.

graph-1

Fig. 2

Determine a conclusion on the effectiveness of the statin treatments in reducing the risk of coronary heart disease for this person.

2d
3 marks

The data was used to generate a report with the claim: "Coronary heart disease can be cured by statins".

Evaluate the claim made. 

3a
3 marks

Extended Only

Fig. 1 below shows the circulatory system of a fish.

Diagram of fish circulatory system showing blood flow through heart, gills, and organs. Labels: heart, artery, vein, ventricle, atrium, capillaries.
Fig. 1

Use Fig. 1 and your own knowledge to compare the structure of the fish circulatory system to that of mammals.

3b
3 marks

Gas exchange in fish occurs in structures known as gills.

Suggest how fish gills support efficient gas exchange.

3c
3 marks

Extended Only

Researchers investigated the effect of stress on heart rate in fish. They decreased water levels in a fish tank until the fish dorsal fins were exposed to air, for a period of 5 minutes, while measuring heart rates. They found that fish heart rates increased during the stress period, and remained elevated for a period of time after water levels returned to normal.

Explain the benefit of an increased heart rate in fish in response to stress.

4a
2 marks

A group of 16-year-old students conducted a classroom experiment to study the effect of physical activity on heart rate.

The students selected four volunteers and measured each student's resting heart rate using a digital pulse monitor. Then, each student ran on a treadmill at a constant speed for 5 minutes. Immediately after the exercise, heart rates were measured again. The process was repeated after 10 minutes of rest to observe recovery.

Identify the independent and dependent variables in this investigation.

4b
3 marks

The results from the investigation in part (a) are shown in Table 1 below:

Table 1

Student

Heart rate (bpm)

Resting

After 5 min run

10 min after exercise

A

72

145

80

B

68

150

92

C

74

162

110

D

70

138

76

Describe the changes in heart rate experienced by students immediately after exercise and after 10 minutes of rest.

4c
3 marks

Extended Tier Only

Explain why the heart rate changes during physical activity.

4d
2 marks

Suggest two ways to improve the validity of the results from the investigation described in part (a).

1a
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2 marks

Fig. 4.1 shows a blue whale, a marine mammal that has a heart weighing up to 600 kg.

A photograph of a blue whale breaching the ocean surface.

Public domain, via rawpixel (opens in a new tab)

Fig. 4.1

In mammals, the wall of the left ventricle is approximately three times thicker than the wall of the right ventricle.

Explain why the muscle wall of the left ventricle is significantly thicker than the muscle wall of the right ventricle.

1b
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4 marks

Blue whales have a double circulatory system.

Explain the advantages of a double circulatory system over a single circulatory system.