Prokaryotic & Eukaryotic Cells (OCR A Level Biology): Revision Note

Exam code: H420

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Lucy Kirkham

Updated on

Comparison of Prokaryotic & Eukaryotic Cells

  • Animal and plant cells are types of eukaryotic cells, whereas bacteria are a type of prokaryote

  • Prokaryotic cells are much smaller than eukaryotic cells (between 100 - 1000 times smaller)

  • Prokaryotic cells also differ from eukaryotic cells in having:

    • A cytoplasm that lacks membrane-bound organelles

    • Their ribosomes are structurally smaller (70 S) in comparison to those found in eukaryotic cells (80 S)

    • No nucleus (instead they have a single circular DNA molecule that is free in the cytoplasm and is not associated with proteins)

    • A cell wall that contains murein (a glycoprotein)

  • In addition, many prokaryotic cells have a few other structures that differentiate them from others and act as a selective advantage, examples of these are:

    • Plasmids

    • Capsules

    • Flagellum

  • Plasmids are small loops of DNA that are separate from the main circular DNA molecule

    • Plasmids contain genes that can be passed between prokaryotes (e.g. genes for antibiotic resistance)

  • Some prokaryotes (e.g. bacteria) are surrounded by a final outer layer known as a capsule. This is sometimes called the slime capsule

    • It helps to protect bacteria from drying out and from attack by cells of the immune system of the host organism

  • Flagellum (plural = flagella) are long, tail-like structure that rotate, enabling the prokaryote to move (a bit like a propeller)

    • Some prokaryotes have more than one

Structures unique to prokaryotic cells

Additional structures unique to prokaryotic cells table, downloadable AS & A Level Biology revision notes
Cell Components- Prokaryotic cell, downloadable AS & A Level Biology revision notes

Prokaryotic cells are often described as being ‘simpler’ than eukaryotic cells, and they are believed to have emerged as the first living organisms on Earth.

  • There are a number of important structural and physiological differences between prokaryotic and eukaryotic cells

    • These differences affect their metabolic processes and how they reproduce

Prokaryotic & Eukaryotic Cells Comparison Table

Comparison of Prokaryotes & Eukaryotes table, downloadable IB Biology revision notes

Examiner Tips and Tricks

You will need to know all the differences between prokaryotic and eukaryotic cells. Remember - the features in the table above are not present in all prokaryotes so keep this in mind when answering exam questions. Also, size is not a structural feature so if you are asked for a structural difference between a prokaryotic and eukaryotic cell don't include size in your answer.

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Lucy Kirkham

Reviewer: Lucy Kirkham

Expertise: Content Creator

Lucy has been a passionate Maths teacher for over 12 years, teaching maths across the UK and abroad helping to engage, interest and develop confidence in the subject at all levels.Working as a Head of Department and then Director of Maths, Lucy has advised schools and academy trusts in both Scotland and the East Midlands, where her role was to support and coach teachers to improve Maths teaching for all.