Variation & Evolution (AQA GCSE Combined Science: Synergy: Life & Environmental Sciences): Flashcards

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  • Define mutation.

Cards in this collection (54)

  • Define mutation.

    A mutation is a random change in the sequence of DNA bases in a gene or chromosome.

  • How can a mutation affect the protein a gene codes for?

    A mutation changes the DNA base sequence, which alters the sequence of amino acids in the protein. This can change the protein's shape and prevent it from functioning correctly.

  • True or False?

    Most mutations result in a significantly altered protein that cannot carry out its function.

    False.

    Most mutations do not alter the protein, or only alter it slightly so that its shape and function remain unchanged. Only a small number of mutations produce a significantly altered protein.

  • Mutations occur .......... and continuously, but their frequency can be increased by exposure to ionising radiation or certain .......... .

    Mutations occur spontaneously and continuously, but their frequency can be increased by exposure to ionising radiation or certain chemicals.

  • Give two types of ionising radiation that can increase the rate of mutations.

    Any two from:

    1. Gamma rays

    2. X-rays

    3. Ultraviolet rays

  • True or False?

    A mutation that changes the shape of an enzyme's active site may prevent the substrate from binding.

    True.

    If a mutation alters the shape of the active site, the substrate can no longer fit and bind, so the enzyme cannot catalyse its reaction.

  • Define genetic variation.

    Genetic variation is the differences in DNA sequences between individuals in a population. All genetic variants arise from mutations.

  • How can a beneficial mutation spread through a population?

    A beneficial mutation gives an individual a survival advantage, so that individual is more likely to reproduce and pass the mutated allele on to offspring. Over generations the advantageous allele becomes more common.

  • True or False?

    Increased exposure to ionising radiation is linked to a higher risk of cancer.

    True.

    Ionising radiation increases the mutation rate in cells. If the mutations affect genes that control cell division, cells may become cancerous.

  • Define evolution.

    Evolution is a change in the inherited characteristics of a population over time through a process of natural selection.

  • What are the four key steps of natural selection?

    1. Variation exists in a population due to mutation.

    2. Individuals with advantageous characteristics are more likely to survive.

    3. Survivors are more likely to reproduce and pass on their alleles.

    4. Over time, advantageous alleles become more common in the population.

  • True or False?

    Darwin's theory of evolution states that all species evolved from simple life forms that first appeared more than three billion years ago.

    True.

    Darwin's theory of natural selection holds that all living things evolved from simple life forms that first developed more than three billion years ago.

  • Individuals in a species show a wide range of .......... caused by differences in genes. Those most suited to the environment have a higher chance of survival and pass their .......... to offspring.

    Individuals in a species show a wide range of variation caused by differences in genes. Those most suited to the environment have a higher chance of survival and pass their alleles to offspring.

  • What role did Alfred Wallace play in our understanding of speciation?

    Alfred Wallace did pioneering work on speciation, and more evidence gathered over time has built on his work to produce our current understanding of how new species form.

  • Define speciation.

    Speciation is the process by which two populations of the same species become so different that they can no longer interbreed to produce fertile offspring, forming two new species.

  • True or False?

    Speciation can occur when two populations of the same species become geographically isolated from each other.

    True.

    A physical barrier (such as a new river or mountain range) can isolate two populations. Different selection pressures then cause them to evolve differently, potentially leading to speciation.

  • Why does geographic isolation lead to populations evolving differently?

    The environment differs on each side of the barrier, creating different selection pressures. Natural selection favours different characteristics in each population, so over many generations they become increasingly distinct.

  • True or False?

    Natural selection and evolution mean the same thing.

    False.

    Evolution refers to changes in species over time, while natural selection is the mechanism by which that change takes place. Evolution is the outcome; natural selection is the process.

  • Define fossil.

    A fossil is the preserved remains of an organism from millions of years ago, found in rocks. Fossils provide evidence for evolution by showing how organisms have changed over time.

  • What does an evolutionary tree show?

    An evolutionary tree is a diagram that shows the relationships between species over evolutionary time. Each new branch represents speciation — the point at which a new species evolved.

  • True or False?

    Two species with more similar DNA base sequences share a more recent common ancestor.

    True.

    The more similar the DNA base sequences of two species, the more closely related they are and the more recent their common ancestor.

  • Antibiotic-resistant strains of bacteria develop because a chance .......... may cause some bacteria to survive antibiotic treatment. These bacteria reproduce, passing on the .......... for resistance.

    Antibiotic-resistant strains of bacteria develop because a chance mutation may cause some bacteria to survive antibiotic treatment. These bacteria reproduce, passing on the genes for resistance.

  • Why are bacteria particularly useful for studying evolution by natural selection?

    Bacteria reproduce very rapidly (roughly every 20 minutes), so evolution occurs over a much shorter time span compared to larger organisms, making it possible to observe the process directly.

  • Define antibiotic resistance.

    Antibiotic resistance is the ability of bacteria to survive and reproduce despite exposure to an antibiotic, arising through natural selection when a chance mutation confers resistance.

  • True or False?

    Bacteria that are not resistant to an antibiotic survive and reproduce more after treatment, out-competing resistant bacteria.

    False.

    After antibiotic treatment, non-resistant bacteria are killed. Only the resistant bacteria survive, reproduce, and pass on resistance genes, so resistant bacteria come to dominate the population.

  • How does the fossil record support the theory of evolution?

    Fossils show how much or how little different organisms have changed over time. By comparing fossils from different geological periods, scientists can track the gradual development of species.

  • Because DNA base sequences code for .......... sequences in proteins, the similarity in .......... sequences between species can also be used to determine how closely related they are.

    Because DNA base sequences code for amino acid sequences in proteins, the similarity in amino acid sequences between species can also be used to determine how closely related they are.

  • Define species.

    A species is a group of organisms that can reproduce with each other to produce fertile offspring.

  • What is the binomial system of naming organisms?

    The binomial system gives each organism a two-part scientific name: the genus (capitalised) followed by the species (lowercase). For example, Homo sapiens. Names are always written in italics.

  • True or False?

    In the binomial system, the genus name begins with a capital letter and the species name begins with a lower case letter.

    True.

    The genus always starts with a capital letter and the species name starts with a lower case letter, e.g. Homo sapiens. Binomial names are written in italics.

  • The sequence of classification from broadest to most specific is: .........., Phylum, Class, Order, Family, .........., Species.

    The sequence of classification from broadest to most specific is: Kingdom, Phylum, Class, Order, Family, Genus, Species.

  • How has DNA sequencing changed the way organisms are classified?

    DNA sequencing allows scientists to compare the base sequences of different species. The more similar the sequences, the more closely related the species. This gives a more scientific and accurate classification than studying physical features alone.

  • Define morphology.

    Morphology is the study of the overall form and shape of an organism. It was one of the original methods used to classify living things before microscopy and DNA analysis became available.

  • True or False?

    Improved microscopes and understanding of biochemical processes led scientists to develop new models of classification.

    True.

    As microscopes improved and understanding of biochemical processes advanced, scientists proposed new classification models, eventually leading to the use of DNA sequences to determine how closely related species are.

  • Why do organisms in the same species share many features?

    Organisms in the same species share features because they descend from a common ancestor and therefore share similar DNA sequences. The more closely related two species are, the more features they share.

  • True or False?

    Classification systems have always been based on DNA analysis since Linnaeus first proposed them.

    False.

    Linnaeus originally classified organisms using physical structure and characteristics. DNA analysis only became possible much later, when new technology allowed scientists to compare base sequences.

  • Define selective breeding.

    Selective breeding (artificial selection) is the process by which humans breed plants and animals for particular genetic traits by choosing parents with desirable characteristics and breeding them together over many generations.

  • Why must selective breeding be repeated over many generations?

    Not all offspring will show the desired characteristics. Only those that do are selected and bred together. This must be repeated over many successive generations before all offspring reliably show the selected traits.

  • True or False?

    Selective breeding has been used by humans for thousands of years to improve food crops and domesticated animals.

    True.

    Humans have used selective breeding for thousands of years to increase the yield and quality of crops (such as rice and maize) and animal products (such as meat and milk).

  • Selective breeding can lead to inbreeding, which reduces the ........... This increases the chance of organisms inheriting harmful .......... or being vulnerable to new diseases.

    Selective breeding can lead to inbreeding, which reduces the gene pool. This increases the chance of organisms inheriting harmful genetic defects or being vulnerable to new diseases.

  • Give two characteristics that cattle or sheep are commonly selectively bred for.

    Any two from:

    1. High milk yield

    2. High quality meat

    3. Good quality wool (sheep)

  • Define inbreeding.

    Inbreeding occurs in selective breeding when closely related individuals are repeatedly bred together, reducing the gene pool and increasing the risk of harmful genetic defects and disease vulnerability.

  • True or False?

    Reducing the gene pool through inbreeding increases the chances of resistant alleles being present in a population.

    False.

    Reducing the gene pool through inbreeding decreases the variety of alleles in the population, so there is less chance of resistant alleles being present. This makes the population more vulnerable to new diseases.

  • Give two characteristics that food crops are commonly selectively bred for.

    Any two from:

    1. Disease resistance

    2. Increased crop yield

    3. Hardiness to weather conditions (e.g. drought tolerance)

  • True or False?

    All modern dog breeds are descended from wolves through selective breeding by humans.

    True.

    All breeds of domestic dog are descended from wolves. Humans have used selective breeding over thousands of years to produce breeds with many different characteristics.

  • Define genetic engineering.

    Genetic engineering is the process of changing the genetic material of an organism by removing, altering, or inserting genes from another organism, which may or may not belong to the same species.

  • What is a vector in genetic engineering, and give one example?

    A vector is used to insert the selected gene into the target organism. One example is a bacterial plasmid (a piece of circular DNA); a virus can also be used as a vector.

  • True or False?

    Genetic engineering is faster than selective breeding.

    True.

    Because genes can be transferred directly between organisms, genetic engineering is much faster than selective breeding, which requires many generations to establish a desired trait.

  • In genetic engineering, .......... are used to isolate the required gene. This gene is then inserted into a .......... which carries it into the target cells.

    In genetic engineering, enzymes are used to isolate the required gene. This gene is then inserted into a vector which carries it into the target cells.

  • What is recombinant DNA?

    Recombinant DNA is the DNA of an organism that now contains DNA from another organism as well. This is produced during genetic engineering when a gene is inserted into a host organism.

  • Define transgenic organism.

    A transgenic organism (genetically modified organism) is one that has received genetic material from another organism through genetic engineering and now expresses the desired characteristics.

  • True or False?

    Genes can only be transferred between organisms of the same species in genetic engineering.

    False.

    In genetic engineering, selected genes can be transferred between organisms that may or may not belong to the same species. This is a key difference from selective breeding.

  • At what stage of development are genes introduced during genetic engineering, and why?

    Genes are introduced at an early stage of development so that the organism develops with the desired characteristics — all cells in the organism will contain the new gene as it divides and grows.

  • True or False?

    An ethical argument about GM technology focuses on whether a technique is safe to carry out in practice.

    False.

    An ethical argument concerns the rights and wrongs of a technology (e.g. whether it is morally acceptable). A practical argument concerns whether the technique is safe or feasible to carry out.

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