Antibiotics & Painkillers (AQA GCSE Combined Science: Trilogy: Biology): Revision Note

Exam code: 8464

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Dr Natalie Lawrence

Updated on

Antibiotics & painkillers

  • There are two types of medication that an individual can take:

    • medicines that treat the cause of the disease, e.g. antibiotics

    • medicines that treat the symptoms of the disease, e.g. painkillers, which do not kill pathogens

  • Antibiotics, such as penicillin, are medicines that help to cure bacterial disease by killing bacteria inside the body

Diagram showing penicillin, an antibiotic that interferes with the building of the bacterial cell wall, acting on a bacterial cell. It prevents proper cell wall formation so that the bacterium swells, ruptures and dies when it grows
Penicillin is an antibiotic that interferes with the cellular processes of the bacterial cell

Using antibiotics

  • Specific bacteria should be treated by specific antibiotics; this is important because

    • antibiotics that are known to be effective against certain bacteria can be used

    • it reduces the likelihood that bacteria will be exposed to multiple antibiotics, so reducing the risk that resistance will develop (see below)

  • Antibiotics are ineffective against viruses, so should not be prescribed to treat viral diseases

    • Viruses reproduce inside body cells

    • It is difficult to develop drugs that kill viruses without also damaging the body’s tissues

Antibiotic resistance

  • Deaths from infectious disease have been greatly reduced by the use of antibiotics in medical treatment

Graph of US infection death rate 1900–1990 showing steep fall after sulfa drugs and penicillin, then slight decline from later medical technologies.

Antibiotics caused US deaths to decline by about 220 per 100,000 in 15 years
All other medical technologies reduced deaths by about 20 per 100,000 over the next 45 years.

Y-axis: US infection death rate per 100,000 population

X-axis: 1940, 1960, 1980
The introduction of antibiotics, such as sulfa and penicillin, has had one of the largest impacts on global health, shown by this example in the USA
  • However, since their discovery and widespread use, antibiotics have been overused, and antibiotic resistance has become a major concern

  • This is a concern because current antibiotics no longer kill these bacteria, some diseases become more common or cannot be treated, and new antibiotics have to be developed, which takes time and money

Preventing development of resistant bacteria

  • To reduce the number of bacteria that are becoming resistant to antibiotics:

    • doctors need to avoid the overuse of antibiotics, prescribing them only when needed – they may test the bacteria first to make sure that they prescribe the correct antibiotic

    • antibiotics should not be used in non-serious infections that the immune system will be able to deal with on its own

    • antibiotics should not be used for viral infections

    • antibiotic use should be reduced in industries such as agriculture – controls are now in place to limit their use in farming

Reducing the spread of resistant strains

  • Good hygiene practices, such as handwashing and the use of hand sanitisers, have reduced the spread of resistant strains of bacteria, such as MRSA, in hospitals

  • The isolation of infected patients also helps to prevent the spread of resistant strains, in particular in surgery wards where MRSA can infect surgical wounds

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Dr Natalie Lawrence

Reviewer: Dr Natalie Lawrence

Expertise: Content Writer

Natalie has a MCantab, Masters and PhD from the University of Cambridge and has tutored biosciences for 14 years. She has written two internationally-published nonfiction books, produced articles for academic journals and magazines, and spoken for TEDX and radio.