Chromosomes, Genes & Proteins (Cambridge (CIE) IGCSE Biology): Revision Note

Exam code: 0610 & 0970

Phil

Written by: Phil

Reviewed by: Jenna Quinn

Updated on

The structure of genes

Inheritance of chromosomes, genes and DNA

  • Inheritance is the transmission of genetic information from generation to generation

  • Chromosomes are located in the nucleus of cells

  • They are thread-like structures of DNA, carrying genetic information in the form of genes

  • A gene is a short length of DNA found on a chromosome that codes for a specific protein

  • This could be a structural protein such as collagen found in skin cells, an enzyme or a hormone

  • Genes control our characteristics as they code for proteins (opens in a new tab) that play important roles in what our cells do

Diagram showing DNA double helix forming a chromosome, labelled as a long DNA strand wrapped round proteins, inside a cell nucleus that contains chromosomes
 Genes are short lengths of DNA that code for a protein; genes are found on chromosomes
  • Alleles are variations of the same gene

  • Humans have two copies of each chromosome (one from each parent), so they have two copies of each gene - and therefore two alleles for each gene

  • One of the alleles for each gene is inherited from the mother and the other from the father

  • The two alleles code for the same characteristic, but may code for different versions of it

  • For example, an individual has two copies of a gene for eye colour, but one allele could code for brown eyes and one allele could code for blue eyes

Examiner Tips and Tricks

The Zoom model is always useful when trying to visualise where you are in a cell, and what molecules are doing what. Imagine a zoom lens that has the power to zoom right out to look at a whole organism, but also to zoom right into individual molecules. This helps in recognising the structures in cell nuclei visible as chromosomes, then zooming in to picture the individual genes and then, the bases that make up the DNA

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Phil

Author: Phil

Expertise: Biology Content Creator

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.

Jenna Quinn

Reviewer: Jenna Quinn

Expertise: Content Creator

Jenna studied at Cardiff University before training to become a science teacher at the University of Bath specialising in Biology (although she loves teaching all three sciences at GCSE level!). Teaching is her passion, and with 10 years experience teaching across a wide range of specifications – from GCSE and A Level Biology in the UK to IGCSE and IB Biology internationally – she knows what is required to pass those Biology exams.