Diffusion in Biology (Cambridge (CIE) IGCSE Biology): Revision Note

Exam code: 0610 & 0970

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Jenna Quinn

Updated on

Diffusion

What is diffusion in biology?

  • Diffusion is the movement of molecules from a region of its higher concentration to a region of its lower concentration

  • Molecules move down a concentration gradient, as a result of their random movement

    Diagram of passive diffusion: molecules move from higher to lower concentration across a cell membrane’s lipid bilayer, from extracellular fluid to cytoplasm.
    Diffusion across the cell membrane
  • For living cells, the principle of the movement down a concentration gradient is the same, but the cell is surrounded by a cell membrane which can restrict the free movement of the molecules

  • The cell membrane is a partially permeable membrane - this means it allows some molecules to cross easily, but others with difficulty or not at all

  • The simplest sort of selection is based on the size of the molecules

  • Diffusion helps living organisms to:

    • Obtain many of their requirements

    • Get rid of many of their waste products

    • Carry out gas exchange for respiration

Examples of diffusion in living organisms 

  • Living organisms obtain various substances they need through diffusion, such as oxygen, carbon dioxide, and other nutrients.

  • It is worth noting that plants require oxygen for respiration at all times, as well as carbon dioxide for photosynthesis when conditions for photosynthesis are right (e.g. enough light and a suitable temperature)

Examples of diffusion in living organisms

Site

Molecules moving

From

To

Small intestine

Digested food products:

  • Glucose

  • Amino acids

  • Fatty acids

  • Glycerol

Lumen of the small intestine

Blood / lymph in villi covering the wall of the small intestine

Leaf

Oxygen

Air spaces between mesophyll cells

Mitochondria in all cells

Leaf

Carbon dioxide

Air spaces between mesophyll cells

Chloroplasts in mesophyll cells

Leaf

Water vapour

Stomatal pores

Air outside stomata

Lungs

Oxygen

Alveolar air space

Blood in capillaries around alveoli

Lungs

Carbon dioxide

Blood in capillaries around alveoli

Alveolar air space

Where does the energy for diffusion come from?

  • All particles move randomly at all times

  • This is known as Brownian motion

  • The energy for diffusion comes from the kinetic energy of this random movement of molecules and ions

Diagram of a closed beaker containing many randomly spaced, moving gas molecules, shown as purple circles with motion lines and labelled “gas molecules”, illustrating Brownian motion
Brownian motion

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Jenna Quinn

Reviewer: Jenna Quinn

Expertise: Content Creator

Jenna studied at Cardiff University before training to become a science teacher at the University of Bath specialising in Biology (although she loves teaching all three sciences at GCSE level!). Teaching is her passion, and with 10 years experience teaching across a wide range of specifications – from GCSE and A Level Biology in the UK to IGCSE and IB Biology internationally – she knows what is required to pass those Biology exams.