Diffusion in Biology (Cambridge (CIE) IGCSE Biology): Revision Note
Exam code: 0610 & 0970
Diffusion
What is diffusion in biology?
Diffusion is the movement of molecules from a region of its higher concentration to a region of its lower concentration
Molecules move down a concentration gradient, as a result of their random movement

Diffusion across the cell membrane For living cells, the principle of the movement down a concentration gradient is the same, but the cell is surrounded by a cell membrane which can restrict the free movement of the molecules
The cell membrane is a partially permeable membrane - this means it allows some molecules to cross easily, but others with difficulty or not at all
The simplest sort of selection is based on the size of the molecules
Diffusion helps living organisms to:
Obtain many of their requirements
Get rid of many of their waste products
Carry out gas exchange for respiration
Examples of diffusion in living organisms
Living organisms obtain various substances they need through diffusion, such as oxygen, carbon dioxide, and other nutrients.
It is worth noting that plants require oxygen for respiration at all times, as well as carbon dioxide for photosynthesis when conditions for photosynthesis are right (e.g. enough light and a suitable temperature)
Examples of diffusion in living organisms
Site | Molecules moving | From | To |
|---|---|---|---|
Small intestine | Digested food products:
| Lumen of the small intestine | Blood / lymph in villi covering the wall of the small intestine |
Leaf | Oxygen | Air spaces between mesophyll cells | Mitochondria in all cells |
Leaf | Carbon dioxide | Air spaces between mesophyll cells | Chloroplasts in mesophyll cells |
Leaf | Water vapour | Stomatal pores | Air outside stomata |
Lungs | Oxygen | Alveolar air space | Blood in capillaries around alveoli |
Lungs | Carbon dioxide | Blood in capillaries around alveoli | Alveolar air space |
Where does the energy for diffusion come from?
All particles move randomly at all times
This is known as Brownian motion
The energy for diffusion comes from the kinetic energy of this random movement of molecules and ions

Unlock more, it's free!
Was this revision note helpful?
Build on this topic