Which Proteins are Synthesised? (Cambridge (CIE) IGCSE Biology): Revision Note

Exam code: 0610 & 0970

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Reviewed by: Jenna Quinn

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Control of gene expression: Extended

  • Expression of a gene means whether that gene is transcribed and translated (opens in a new tab) in a particular cell or not

  • Most genes are not expressed in a particular cell; they are 'switched off'

  • Only the genes whose proteins are vital to that cell's function are expressed ('switched on')

Protein synthesis, IGCSE & GCSE Biology revision notes
Protein synthesis
  • In this way, DNA controls cell function by controlling the production of proteins

  • The proteins may be enzymes, antibodies, or receptors for neurotransmitters

  • Although all body cells in an organism contain the same genes, many genes in a particular cell are not expressed because the cell only makes the specific proteins it needs 

Diagram of translation showing mRNA codons in a ribosome, tRNA anticodons bringing amino acids, and peptide bonds forming a growing polypeptide chain.
The triplet code of DNA (carried by mRNA) is read by the ribosome and amino acids are attached together in a specific sequence to form the protein 

Haploid and diploid cells

  • All humans have 23 different chromosomes in each cell

  • Human body cells, not including the gametes (sex cells), contain two copies of each chromosome, leading to a total of 46 chromosomes

  • Nuclei with two sets of chromosomes are known as diploid nuclei

  • The gametes (egg and sperm cells) only have one copy of each chromosome, meaning they have a total of 23 chromosomes in each cell

  • Nuclei with one set of unpaired chromosomes are known as haploid nuclei

Examiner Tips and Tricks

An easy way to remember the difference between haploid and diploid is to remember:

Haploid = Half the normal number of chromosomes

It’s worth noting that the human diploid chromosome number is 46. In an exam, you may be given information about a different species, with a different number of chromosomes. Make sure you read exam questions carefully.


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Phil

Author: Phil

Expertise: Biology Content Creator

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.

Jenna Quinn

Reviewer: Jenna Quinn

Expertise: Content Creator

Jenna studied at Cardiff University before training to become a science teacher at the University of Bath specialising in Biology (although she loves teaching all three sciences at GCSE level!). Teaching is her passion, and with 10 years experience teaching across a wide range of specifications – from GCSE and A Level Biology in the UK to IGCSE and IB Biology internationally – she knows what is required to pass those Biology exams.