Chromosomes (AQA GCSE Biology): Revision Note

Exam code: 8461

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Dr Natalie Lawrence

Updated on

Chromosomes: Basics

  • In eukaryotic cells, the nucleus contains thread-like structures called chromosomes

  • Chromosomes are made from highly coiled strands of relatively long DNA. Each chromosome is made from one DNA molecule

  • In the body cells of diploid organisms, chromosomes are normally found in pairs

  • One chromosome from each pair is inherited from the mother, the other from the father

  • Different species of organisms have different numbers of chromosomes in their nuclei

    • Humans have 46 chromosomes in the nucleus of all their body cells, found in 23 pairs

    • Horses have 64 chromosomes in 32 pairs

    • Red blood cells are an exception – they lose their nuclei and therefore have no chromosomes

  • Before a cell can divide, its genetic material needs to be doubled. This results in the characteristic ‘X’ shaped chromosomes seen in micrographs of cells preparing to divide

Diagram showing an uncoiled chromosome inside a nucleus, then condensed into a chromosome in preparation for mitosis, then the X-shaped chromosome formed after replication consisting of two chromatids
Chromosomes are usually uncoiled: when a cell prepares to divide they condense into more visible structures

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Dr Natalie Lawrence

Reviewer: Dr Natalie Lawrence

Expertise: Content Writer

Natalie has a MCantab, Masters and PhD from the University of Cambridge and has tutored biosciences for 14 years. She has written two internationally-published nonfiction books, produced articles for academic journals and magazines, and spoken for TEDX and radio.