The Brain (AQA GCSE Biology): Revision Note

Exam code: 8461

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Dr Natalie Lawrence

Updated on

The brain: Basics

  • The brain, alongside the spinal cord, is part of our central nervous system

  • The brain is made of billions of interconnected neurones and is responsible for controlling complex behaviours

  • Within the brain are different regions that carry out different functions

Structure of the brain

  • Scientists have discovered that different regions of the brain seem to be responsible for controlling different functions

  • These include the following regions:

    • The cerebral cortex:

      • is the outer layer of the brain, which is divided into two hemispheres

      • is highly folded

      • is responsible for higher-order processes such as intelligence, memory, consciousness and personality

    • The cerebellum:

      • is underneath the cerebral cortex

      • is responsible for balance, muscle coordination and movement

    • The medulla:

      • is the region which controls unconscious activities such as heart rate and breathing

Diagram of a cross-section of the human brain showing the locations and functions of major structures. The cerebral cortex forms the outer layer of neural tissue and is responsible for consciousness, memory, intelligence and language. The hypothalamus is shown near the centre of the brain, above the pituitary gland. The pituitary gland regulates many body functions by controlling the activity of other glands. The cerebellum is located at the back and lower part of the brain and is responsible for muscle coordination and movement. The medulla is at the base of the brain and controls unconscious activities such as breathing and heart rate. The spinal cord extends downwards from the brain and forms part of the central nervous system (CNS).
The main regions of the brain have different functions, including controlling conscious thought, movement, hormone release and unconscious activities

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Investigating the brain

Higher Tier Only

  • The brain is an incredibly complex and delicate organ – this makes it extremely difficult for neuroscientists to study it to find out how it works

  • Science's understanding is limited because the brain is so complex and different regions cannot be studied in isolation

  • This limited understanding means that treating brain damage and disease is very difficult

    • In addition, any potential treatment carries risks of further damage occurring, which can lead to increased problems

    • Accidental damage could lead to speech or motor issues, or changes to personality which are permanent

Mapping regions of the brain

  • Neuroscientists have been able to map the regions of the brain to particular functions by studying patients with brain damage, electrically stimulating different parts of the brain and using MRI scanning techniques

  • Patients with brain damage can be studied to see what effect it has on them physically or on their personality or capabilities

    • The most famous example of this is Phineas Gage, a rail construction worker who survived a large iron rod being driven completely through his head – his frontal left lobe was completely destroyed, and his personality and temperament changed drastically

  • Tiny electrodes can be pushed into different parts of the brain

  • Small jolts of electricity stimulate these regions and the effects can be observed

    • For example, if a region in the brain responsible for movement is stimulated, the movement caused can be observed

  • MRI scanners are very important diagnostic tools used to study the brain and other regions of the body using magnetic fields and the effect these have on protons in the water molecules of the body

    • Functional MRIs can produce images of different regions of the brain that are active during different activities like listening to music or recalling a memory (the scanners can detect changes in blood flow – more active regions of the brain have increased blood flow)

Examiner Tips and Tricks

In the exam you may be asked to evaluate the benefits and risks of procedures carried out on the brain and nervous system.

The benefits of procedures being carried out usually involve improving the quality of someone’s life (as the procedure is used to treat a disorder of some kind) but there are risks of more permanent damage, some of these will be because we still don’t fully understand how the brain and nervous system works.

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Dr Natalie Lawrence

Reviewer: Dr Natalie Lawrence

Expertise: Content Writer

Natalie has a MCantab, Masters and PhD from the University of Cambridge and has tutored biosciences for 14 years. She has written two internationally-published nonfiction books, produced articles for academic journals and magazines, and spoken for TEDX and radio.