Blood Vessels & Blood (AQA GCSE Biology): Revision Note

Exam code: 8461

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Dr Natalie Lawrence

Updated on

Blood vessels

  • The body contains three different types of blood vessels:

    • arteries: transport blood away from the heart

    • veins: transport blood to the heart

    • capillaries: links arteries to veins and are the site of substance exchange with the body cells

Examiner Tips and Tricks

Remember that:

  • arteries carry blood away from the heart

  • veins carry blood into the heart

Blood vessel structures

  • The structure of each type of blood vessel relates to its function

  • Arteries must withstand and maintain high pressures generated by the contracting heart muscle; features that enable this include:

    • thick walls that contain muscle for strength and elastic tissue for stretch and recoil

    • a narrow lumen to maintain high blood pressure

  • Veins carry a large volume of blood at low-pressure; features that enable this include:

    • a large lumen to accomodate the large volume of blood

    • thinner walls, as they do not need to withstand high pressure

    • valves to prevent backflow of blood

  • Capillaries carry blood to the cells of the body, supplying required substances and removing waste; features that enable this include:

    • walls one cell thick, minimising the diffusion distance for exchange

    • very narrow lumen to slow blood flow, allowing time for exchange to occur

Diagram comparing artery and vein structure as well as capillaries:
- The arteries have small lumens and thick walls with a thicker layer of smooth muscle compares to veins because they withstand higher pressure
- Both artery and vein walls have elastic fibres
- There are valves in veins because they are low pressure vessels
- Capillaries in the body tissues are where exchange between the blood and tissues takes place
The blood vessels form a continuous network; the structure of each allows it to carry out its function

Use this image

Examiner Tips and Tricks

Never say that capillaries have 'thin cell walls' as this is incorrect; capillaries have walls that are one cell thick.

Rate calculations: Blood flow

  • The rate of blood flow can be calculated if the volume of blood flow and the time is known

Worked Example

If 2460 ml of blood flows through a blood vessel in 4 minutes, what is the rate of blood flow?

Answer:

Step 1: Rate = volume of blood / number of minutes

= 2460 / 4

= 615 ml/minute

Step 2: From this it may be determined how much blood flows through the same vessel in one hour

= rate of blood flow (ml/min) x 60

= 615 x 60 = 36 900 ml

Loading video: 9.1.14 AQA GCSE Blood

Structure & function: Blood

  • The role of blood is to transport useful substances to every cell of the body, and to remove harmful waste substances

  • Blood is a tissue that contains:

    • plasma

    • red blood cells

    • white blood cells

    • platelets

Components of the blood

Plasma

  • Plasma is the straw-coloured liquid part of the blood in which the cells are suspended

  • It transports dissolved substances, including carbon dioxide (from respiring cells to the lungs), glucose and amino acids (from the small intestine to cells), urea (from the liver to the kidneys), hormones, antibodies and ions

  • It also carries the blood cells and transfers heat around the body

  • Always name the substance: 'nutrients' and 'waste' do not get the mark

Red blood cells

  • Red blood cells carry oxygen around the body

  • They have several features that aid their function:

    • a biconcave disc shape

      • The biconcave shape gives red blood cells a large surface to volume ratio; this is a key adaptation to maximise the efficiency of diffusion of gases into and out of the cell

    • haemoglobin

      • This is a protein that binds to oxygen, allowing it to be transported around the body

    • no nucleus

      • This maximises the space available for haemoglobin

Diagram of red blood cell showing biconcave shape, cell membrane, and cytoplasm containing haemoglobin, highlighted with labelled arrows.
Red blood cells are specialised for oxygen transport.

White blood cells

  • White blood cells are part of the immune system, responsible for defending the body from infection by recognising and destroying pathogens

  • white blood cells defend the body by:

Platelets

  • Platelets are fragments of cells (they contain cytoplasm but no nucleus)

  • When damage to a blood vessel occurs, the platelets are involved in forming a blood clot to prevent blood loss

Diagram showing blood composition: 55% yellow plasma and 45% cells, including labelled red and white blood cells and platelets within a circular blood sample
The human blood is composed largely of plasma and red blood cells, with white blood cells and platelets making up a smaller proportion of total volume

Use this image

Recognising blood cells

  • An exam question may include a photograph or diagram and ask the identity of the types of blood cell present

  • Observing and drawing cells under the microscope is an important skill to develop

  • To identify the cells: white blood cells are larger than red blood cells and are the only blood cells with a nucleus (often lobed); red blood cells are biconcave discs with no nucleus; platelets are much smaller cell fragments with no nucleus

Diagram of blood showing many red blood cells, a few scattered platelets, and fewer larger white blood cells with lobed nuclei on a white background
This is an image of how blood might look under a microscope: white blood cells are larger than red blood cells, while platelets are the smallest of the three components

Use this image

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Dr Natalie Lawrence

Reviewer: Dr Natalie Lawrence

Expertise: Content Writer

Natalie has a MCantab, Masters and PhD from the University of Cambridge and has tutored biosciences for 14 years. She has written two internationally-published nonfiction books, produced articles for academic journals and magazines, and spoken for TEDX and radio.