Diffusion (AQA GCSE Biology): Revision Note

Exam code: 8461

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Dr Natalie Lawrence

Updated on

Transport: Basics

  • In order for any organism to function properly, it needs to exchange substances such as food molecules and waste products between itself and its environment

  • This exchange of substances occurs across the cell membrane

  • There are three transport processes that living organisms use for exchange: diffusion, osmosis and active transport

Loading video: 3.1.1 AQA GCSE Diffusion

Diffusion: Basics

What is diffusion?

  • Diffusion is the spreading out of the particles of any substance in solution, or particles of a gas, resulting in a net movement of particles from an area of higher concentration to an area of lower concentration

  • This means that particles in a solution or a gas are always moving about randomly

  • If there happen to be more particles in one area/region, then there tends to be an overall (net) movement of particles from this region of higher concentration to a region where there are fewer particles (an area of lower concentration)

Diagram showing perfume particles spreading from a high to a low concentration across a room.
Diffusion of perfume particles through a room is one of the simplest examples of diffusion

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  • Diffusion is an entirely passive process; the movement of particles in a fluid is dependent on how much kinetic energy they have

    • The higher the temperature, the more kinetic energy particles have and therefore the faster they can move by diffusion

Diffusion in living organisms

  • All cells are surrounded by a cell membrane which separates the inside of the cell from its outside environment

  • Substances have to be able to diffuse through the cell membrane to enter or exit the cell unaided (there are other ways for substances to get in)

  • Not all substances are able to diffuse across the cell membrane which is why it is described as being ‘partially permeable’; some substances are able to enter or leave the cell whilst others aren’t

    • For example, oxygen and carbon dioxide can diffuse across the cell membrane during gas exchange whereas the carbohydrate starch cannot (it’s too big)

Diagram showing how the cell membrane acts as a barrier across which substances have to be able to move to get into or out of a cell. Glucose is able to cross the partially permeable  lipid bilayer of the membrane via diffusion from higher to lower concentration. Starch cannot cross the membrane.
The cell membrane acts as a barrier across which substances have to be able to move to get into or out of a cell

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Diffusion: Examples

  • Examples of substances that enter cells by diffusion:

    • Oxygen must diffuse into cells for aerobic respiration

    • Carbon dioxide must diffuse into photosynthesising plant cells to be available for photosynthesis

  • Examples of substances that leave cells by diffusion:

    • Liver cells break down excess amino acids into the waste product urea which is highly toxic and must diffuse out of cells to be excreted by the kidneys

    • Carbon dioxide produced by aerobic respiration must diffuse out of cells

  • In both the transport of substances into and out of a cell by diffusion, the movement is driven by a concentration gradient existing between the cell and its immediate environment

  • If the direction of that concentration gradient changes, the movement of a substance by diffusion will also change

Examiner Tips and Tricks

Remember that a photosynthesising leaf cell will likely have a lower carbon dioxide concentration on a bright day compared to its environment, as carbon dioxide is used in photosynthesis faster than it is produced in aerobic respiration.

You should expect the gradient to reverse at night, when the plant is not photosynthesising but is still respiring, so the carbon dioxide concentration inside the same leaf cell will be higher than the environment.

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Dr Natalie Lawrence

Reviewer: Dr Natalie Lawrence

Expertise: Content Writer

Natalie has a MCantab, Masters and PhD from the University of Cambridge and has tutored biosciences for 14 years. She has written two internationally-published nonfiction books, produced articles for academic journals and magazines, and spoken for TEDX and radio.