Lifestyle & Non-Communicable Diseases (AQA GCSE Biology): Revision Note

Exam code: 8461

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Dr Natalie Lawrence

Updated on

Risk factors

  • Risk factors are linked to an increased rate of a disease

  • Exposure to a risk factor doesn’t guarantee that an individual will suffer a disease (a person who smokes regularly isn’t guaranteed to develop lung cancer but their risk compared to someone who doesn’t smoke is much, much higher)

  • Certain risk factors correlate with certain diseases (are related to them) but correlations are not always causations

  • Risk factors can be:

    • Aspects of a person’s lifestyle, such as the food they eat or whether or not they drink alcohol

    • Substances in the person’s body or environment, such as air pollution in a crowded city or asbestos in old buildings

Causal mechanisms & risk factors

  • A causal mechanism has been proven for some risk factors, but not in others

Risk Factor

Disease Risk Factor is Linked to

Explanation of how Risk Factor may Cause Disease

Smoking

Lung disease, lung cancer and cardiovascular disease

Chemicals in cigarette smoke (such as tar and nicotine) damage the alveoli in the lungs and the endothelial lining of the arteries.

Obesity caused by a poor diet

Type 2 diabetes

Excess consumption of sugar as a result of a poor diet reduces the body’s sensitivity to insulin.

Consuming alcohol

Liver disease and impaired brain function

The breakdown of alcohol by cells of the liver produces substances which can be toxic to liver cells in high concentrations. The neurones of the brain are also damaged by alcohol, reducing brain function.

Exposure to carcinogens

Cancer

Exposure to ionising radiation (e.g. X-rays) or certain chemicals can damage DNA in cells, leading to uncontrolled cell division, causing cancer.

Smoking and consuming alcohol while pregnant

Poor development of foetus (unborn baby)

Carbon monoxide in cigarette smoke reduces the amount of oxygen transported around the mother’s body, reducing the oxygen delivered to the foetus. Substances in alcohol can impair the development of the brain in a foetus.

  • Many diseases are caused by the interaction of a number of factors; the chance of developing cardiovascular disease is higher in individuals who have a poor diet high in cholesterol (fat), don’t exercise regularly and smoke – because all of these behaviours increase the likelihood of damage occurring to the arteries

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Dr Natalie Lawrence

Reviewer: Dr Natalie Lawrence

Expertise: Content Writer

Natalie has a MCantab, Masters and PhD from the University of Cambridge and has tutored biosciences for 14 years. She has written two internationally-published nonfiction books, produced articles for academic journals and magazines, and spoken for TEDX and radio.